†Department of Chemistry and Biochemistry, University of Missouri-St. Louis, One University Boulevard, St. Louis, Missouri 63121, United States.
Org Lett. 2015 May 15;17(10):2382-4. doi: 10.1021/acs.orglett.5b00899. Epub 2015 Apr 30.
The first synthesis of the repeating unit of S. aureus capsular polysaccharide type 8 is described. The repeating unit is an unusual trisaccharide sequence of three uncommon sugars, all connected via 1,2-cis linkages. The synthetic trisaccharide was equipped with capping methyl groups at the points of propagation of the polysaccharide sequence.
本文描述了金黄色葡萄球菌荚膜多糖 8 型重复单元的首次全合成。该重复单元是一个由三个罕见糖组成的非同寻常的三糖序列，均通过 1,2-顺式键连接。合成的三糖在多糖序列的生长点上带有封端甲基。
