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2015年印第安纳州与注射使用羟考酮相关的艾滋病毒感染社区疫情

Community Outbreak of HIV Infection Linked to Injection Drug Use of Oxymorphone--Indiana, 2015.

作者信息

Conrad Caitlin, Bradley Heather M, Broz Dita, Buddha Swamy, Chapman Erika L, Galang Romeo R, Hillman Daniel, Hon John, Hoover Karen W, Patel Monita R, Perez Andrea, Peters Philip J, Pontones Pam, Roseberry Jeremy C, Sandoval Michelle, Shields Jessica, Walthall Jennifer, Waterhouse Dorothy, Weidle Paul J, Wu Hsiu, Duwve Joan M

出版信息

MMWR Morb Mortal Wkly Rep. 2015 May 1;64(16):443-4.

PMID:25928470
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4584812/
Abstract

On January 23, 2015, the Indiana State Department of Health (ISDH) began an ongoing investigation of an outbreak of human immunodeficiency virus (HIV) infection, after Indiana disease intervention specialists reported 11 confirmed HIV cases traced to a rural county in southeastern Indiana. Historically, fewer than five cases of HIV infection have been reported annually in this county. The majority of cases were in residents of the same community and were linked to syringe-sharing partners injecting the prescription opioid oxymorphone (a powerful oral semi-synthetic opioid analgesic). As of April 21, ISDH had diagnosed HIV infection in 135 persons (129 with confirmed HIV infection and six with preliminarily positive results from rapid HIV testing that were pending confirmatory testing) in a community of 4,200 persons.

摘要

2015年1月23日,印第安纳州卫生部(ISDH)在该州疾病干预专家报告了11例确诊的人类免疫缺陷病毒(HIV)感染病例后,开始对一起HIV感染疫情展开持续调查。这些病例均追溯至印第安纳州东南部的一个乡村县。从历史数据来看,该县域内每年报告的HIV感染病例数不足5例。大部分病例来自同一社区的居民,且与共用注射器的伙伴有关,这些伙伴注射的是处方类阿片类药物羟考酮(一种强效口服半合成阿片类镇痛药)。截至4月21日,在一个仅有4200人的社区中,ISDH已诊断出135人感染HIV(129人确诊感染,6人HIV快速检测初步呈阳性,结果有待确认检测)。