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物质使用的感染性并发症：一项针对住院退伍军人的回顾性队列研究。

Infectious Complications of Substance Use: A Retrospective Cohort Study of Hospitalized Veterans.

作者信息

Harvey Leah, Abdulkerim Hassen, Strymish Judith, Ryan Samantha K, Boudreau Jacqueline, Gifford Allen, Hyde Justeen, Branch-Elliman Westyn

机构信息

Division of Infectious Diseases, Department of Medicine, Alpert School of Medicine at Brown University, Providence, Rhode Island, USA.

Center for Health Optimization and Implementation Research, VA Boston Healthcare System, US Department of Veterans Affairs . Boston, Massachusetts, USA.

出版信息

Open Forum Infect Dis. 2025 May 17;12(6):ofaf301. doi: 10.1093/ofid/ofaf301. eCollection 2025 Jun.

DOI:10.1093/ofid/ofaf301
PMID:40476030
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12138505/
Abstract

Invasive bacterial infections (IBI) associated with drug use are increasing, but the full disease burden remains unknown. We characterized national trends in the prevalence of IBI among veterans with evidence of substance use using a large, national cohort. High rates of IBI highlight a need for more comprehensive infection reduction strategies, including emphasis on gram-negative infections.

摘要

与药物使用相关的侵袭性细菌感染（IBI）正在增加，但完整的疾病负担仍不清楚。我们使用一个大型全国队列，对有药物使用证据的退伍军人中IBI患病率的全国趋势进行了描述。IBI的高发病率凸显了需要更全面的感染减少策略，包括对革兰氏阴性菌感染的重视。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/751e/12138505/87b6f13ee9c6/ofaf301f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/751e/12138505/10a30aaa920a/ofaf301_ga.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/751e/12138505/3f054b186d8a/ofaf301f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/751e/12138505/87b6f13ee9c6/ofaf301f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/751e/12138505/10a30aaa920a/ofaf301_ga.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/751e/12138505/3f054b186d8a/ofaf301f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/751e/12138505/87b6f13ee9c6/ofaf301f2.jpg

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本文引用的文献

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Six Moments of Infection Prevention in Injection Drug Use: An Educational Toolkit for Clinicians.注射吸毒中预防感染的六个时刻：临床医生教育工具包
Open Forum Infect Dis. 2022 Jan 6;9(2):ofab631. doi: 10.1093/ofid/ofab631. eCollection 2022 Feb.
2
Prevalence of substance use and substance-related disorders among US Veterans Health Administration patients.美国退伍军人事务部患者中物质使用和相关障碍的流行情况。
Drug Alcohol Depend. 2021 Aug 1;225:108791. doi: 10.1016/j.drugalcdep.2021.108791. Epub 2021 May 31.
3
Association of skin infections with sharing of injection drug preparation equipment among people who inject drugs.
共用注射毒品准备设备与注射毒品者皮肤感染的关联。
Int J Drug Policy. 2021 Aug;94:103198. doi: 10.1016/j.drugpo.2021.103198. Epub 2021 Mar 18.
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Rise in Endocarditis-related Hospitalizations in Young People Who Use Opioids: A Call to Action.使用阿片类药物的年轻人中与心内膜炎相关的住院人数上升：行动呼吁。
Clin Infect Dis. 2021 May 18;72(10):1782-1783. doi: 10.1093/cid/ciaa376.
5
Beyond Antibiotics: A Practical Guide for the Infectious Disease Physician to Treat Opioid Use Disorder in the Setting of Associated Infectious Diseases.超越抗生素：传染病医生在合并感染性疾病情况下治疗阿片类物质使用障碍的实用指南。
Open Forum Infect Dis. 2019 Dec 24;7(1):ofz539. doi: 10.1093/ofid/ofz539. eCollection 2020 Jan.
6
Associations between perceived illicit fentanyl use and infectious disease risks among people who inject drugs.注射吸毒人群中感知到的非法芬太尼使用与传染病风险之间的关联。
Int J Drug Policy. 2019 Dec;74:299-304. doi: 10.1016/j.drugpo.2019.10.004. Epub 2019 Nov 13.
7
Trends in Drug Use-Associated Infective Endocarditis and Heart Valve Surgery, 2007 to 2017: A Study of Statewide Discharge Data.2007 年至 2017 年药物滥用相关性感染性心内膜炎及心脏瓣膜手术趋势：全州出院数据研究。
Ann Intern Med. 2019 Jan 1;170(1):31-40. doi: 10.7326/M18-2124. Epub 2018 Dec 4.
8
Estimating Prevalence of Hepatitis C Virus Infection in the United States, 2013-2016.估计 2013-2016 年美国丙型肝炎病毒感染的流行率。
Hepatology. 2019 Mar;69(3):1020-1031. doi: 10.1002/hep.30297. Epub 2018 Nov 6.
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Subst Abuse Rehabil. 2017 Aug 30;8:69-77. doi: 10.2147/SAR.S116720. eCollection 2017.