脑血管造影术后的短暂性皮质盲

Transient cortical blindness following cerebral angiography.

作者信息

Shyn P B, Bell K A

出版信息

J La State Med Soc. 1989 Nov;141(11):35-7.

Abstract

Transient cortical blindness following cerebral angiography was previously assumed to result from embolism or other factors impairing cortical perfusion during angiography. Contrast medium-induced disruption of the blood-brain barrier and a direct neurotoxic effect by contrast media have been proposed as a potential mechanism of neurotoxicity. Support of this concept has been provided by reports that demonstrate blood-brain barrier damage with postangiography computerized tomography in patients experiencing various acute neurologic sequelae of cerebral angiography including one case of transient cortical blindness. We report a case of transient cortical blindness following cerebral angiography in which computerized tomography documents blood-brain barrier disruption limited to the occipital lobes.

摘要

脑血管造影术后出现的短暂性皮质盲，以往认为是由血管造影期间的栓塞或其他损害皮质灌注的因素所致。造影剂引起的血脑屏障破坏以及造影剂的直接神经毒性作用，已被提出作为神经毒性的一种潜在机制。有报告称，在经历脑血管造影各种急性神经后遗症（包括一例短暂性皮质盲）的患者中，血管造影术后计算机断层扫描显示血脑屏障受损，这为这一概念提供了支持。我们报告一例脑血管造影术后短暂性皮质盲病例，其中计算机断层扫描显示血脑屏障破坏仅限于枕叶。