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腹腔镜袖状胃切除术后2年体重减轻的预测因素。

Predictors of weight loss 2 years after laparoscopic sleeve gastrectomy.

作者信息

Martin David J, Lee Crystal M Y, Rigas Georgia, Tam Charmaine S

机构信息

Concord and Royal Prince Alfred Hospitals, University of Sydney, Sydney, New South Wales, Australia.

Strathfield Private Hospitals, University of Sydney, Sydney, New South Wales, Australia.

出版信息

Asian J Endosc Surg. 2015 Aug;8(3):328-32. doi: 10.1111/ases.12193. Epub 2015 Apr 30.

Abstract

INTRODUCTION

Despite the rapidly increasing popularity of laparoscopic sleeve gastrectomy (LSG), there is limited data examining weight loss more than 1 year after the procedure. There have also been few studies examining baseline predictors of weight loss after LSG. We aimed to examine the percentage of excess weight loss (%EWL) in patients 2 years after LSG and identify baseline predictors of %EWL.

METHODS

Electronic records from university hospitals were available for 292 patients who underwent LSG (205 women; mean age, 41.5 ± 11.1 years; mean weight, 126.5 ± 27.5 kg; mean BMI, 45.5 ± 7.5 kg/m(2) ). Variables assessed for predictive effect were baseline age, sex, BMI, presence of comorbidities (diabetes, hypertension, or obstructive sleep apnea), the amount of weight loss induced by a very low-calorie diet before surgery, and the number of clinic appointments attended over the 2 years. We performed linear regression and mixed model analyses between predictor variables and %EWL at 2 years.

RESULTS

Adjusted %EWL was 31% at 2 weeks, 49% at 3 months, 64% at 6 months, 70% at 9 months, 76% at 12 months, 79% at 18 months, and 79% at 2 years. Multivariate analysis showed that lower baseline BMI, absence of hypertension, and greater clinic attendance predicted better %EWL (r(2)  = 0.11).

CONCLUSION

Longer-term follow-up studies of weight loss post LSG are required to assist with patient care and management.

摘要

引言

尽管腹腔镜袖状胃切除术(LSG)的普及程度迅速提高,但关于该手术后1年以上体重减轻情况的数据有限。此外,很少有研究探讨LSG术后体重减轻的基线预测因素。我们旨在研究LSG术后2年患者的超重减轻百分比(%EWL),并确定%EWL的基线预测因素。

方法

大学医院的电子记录可供292例行LSG手术的患者使用(205名女性;平均年龄41.5±11.1岁;平均体重126.5±27.5千克;平均BMI 45.5±7.5千克/平方米)。评估预测效果的变量包括基线年龄、性别、BMI、合并症(糖尿病、高血压或阻塞性睡眠呼吸暂停)的存在情况、术前极低热量饮食引起的体重减轻量以及2年内就诊的门诊次数。我们对预测变量与2年时的%EWL进行了线性回归和混合模型分析。

结果

调整后的%EWL在2周时为31%,3个月时为49%,6个月时为64%,9个月时为70%,12个月时为76%,18个月时为79%,2年时为79%。多变量分析表明,较低的基线BMI、无高血压以及更多的门诊就诊次数预示着更好的%EWL(r² = 0.11)。

结论

需要对LSG术后体重减轻进行长期随访研究,以协助患者护理和管理。

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