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[伴有眼部受累的结节病]

[Sarcoidosis with ocular involvement].

作者信息

Chung Y M, Yeh T S, Tsai S J

出版信息

Taiwan Yi Xue Hui Za Zhi. 1989 Aug;88(8):850-2, 842.

PMID:2592950
Abstract

A 28-year-old Chinese woman having sarcoidosis with ocular involvement was reported. She demonstrated bilateral hilar lymphadenopathy in a chest X-ray which was taken for a cough. Transbronchial lung biopsy revealed noncaseating epithelioid granulomas. Blurred vision occurred 8 months later when conjunctival follicle-like masses, granulomatous keratic precipitates, iridocyclitis, "snow-ball" vitreous opacity, and retinal periphlebitis developed in both eyes. Biopsy of the conjunctival follicle-like masses revealed noncaseating granulomas composed of epithelioid cells and multinuclear giant cells, typical of sarcoidosis. The ocular lesions waned under topical steroid treatment and vision improved. This is the only case with an ocular involvement among the 10 cases of sarcoidosis seen during the past 20 years at the Taipei Veterans General Hospital.

摘要

报告了一名28岁患有结节病并累及眼部的中国女性。她因咳嗽进行胸部X线检查时显示双侧肺门淋巴结肿大。经支气管肺活检显示非干酪样上皮样肉芽肿。8个月后,双眼出现结膜滤泡样肿物、肉芽肿性角膜后沉着物、虹膜睫状体炎、“雪球样”玻璃体混浊和视网膜静脉周围炎,导致视力模糊。结膜滤泡样肿物活检显示由上皮样细胞和多核巨细胞组成的非干酪样肉芽肿,这是结节病的典型表现。眼部病变在局部类固醇治疗下消退,视力改善。这是台北荣民总医院在过去20年中所见的10例结节病中唯一累及眼部的病例。

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