Alfaar Ahmad S, Zamzam Manal, Abdalla Badr, Magdi Ranin, El-Kinaai Naglaa
Departments of *Research §Pediatric Oncology ∥Pathology, Children's Cancer Hospital †Cairo University Hospitals, Faculty of Medicine, Cairo University, Cairo, Egypt ‡Faculty of Medicine, Ulm University, Ulm, Germany.
J Pediatr Hematol Oncol. 2015 Aug;37(6):433-7. doi: 10.1097/MPH.0000000000000346.
In the span of the last 48 years, only 33 cases of children with orbital Ewing sarcoma have been reported. This study is to present 3 cases that were admitted to Children's Cancer Hospital Egypt 57357, during the period from 2009 to 2013. We have 2 cases treated using the hospital standard Ewing sarcoma treatment protocol, to completion, whereas the third discontinued treatment. All tumors have confirmed CD99 positivity, although translocation (11;22) was positive in 1 patient and negative in the third. With earlier diagnosis and adequate surgical resection and integration of chemotherapy and radiotherapy 1 patient survived for about 4 years, whereas the other 2 cases died due to disease progression or recurrence.
在过去的48年里，仅报告了33例儿童眼眶尤文肉瘤病例。本研究旨在介绍2009年至2013年期间收治于埃及57357儿童医院的3例病例。我们有2例按照医院尤文肉瘤标准治疗方案完成了治疗，而第3例中断了治疗。所有肿瘤均证实CD99阳性，尽管1例患者的（11；22）易位呈阳性，第3例为阴性。通过早期诊断、充分的手术切除以及化疗和放疗的综合应用，1例患者存活了约4年，而另外2例因疾病进展或复发死亡。
