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Androgen-dependent loss of muscle BDNF mRNA in two mouse models of SBMA.
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Contractile dysfunction in muscle may underlie androgen-dependent motor dysfunction in spinal bulbar muscular atrophy.
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Pre-clinical symptoms of SBMA may not be androgen-dependent: implications from two SBMA mouse models.
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Antiandrogen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy.
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Recovery of function in a myogenic mouse model of spinal bulbar muscular atrophy.
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Trophic effects of brain-derived neurotrophic factor blockade in an androgen-sensitive neuromuscular system.
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Non-Cell-Autonomous Regulation of Retrograde Motoneuronal Axonal Transport in an SBMA Mouse Model.
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Defects in Neuromuscular Transmission May Underlie Motor Dysfunction in Spinal and Bulbar Muscular Atrophy.
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The Regulation of the Small Heat Shock Protein B8 in Misfolding Protein Diseases Causing Motoneuronal and Muscle Cell Death.
Front Neurosci. 2019 Aug 2;13:796. doi: 10.3389/fnins.2019.00796. eCollection 2019.
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Pre-clinical symptoms of SBMA may not be androgen-dependent: implications from two SBMA mouse models.
Hum Mol Genet. 2018 Jul 15;27(14):2425-2442. doi: 10.1093/hmg/ddy142.
8
Non-Cell-Autonomous Regulation of Retrograde Motoneuronal Axonal Transport in an SBMA Mouse Model.
eNeuro. 2016 Aug 10;3(4). doi: 10.1523/ENEURO.0062-16.2016. eCollection 2016 Jul-Aug.
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Neuromuscular junctions are pathological but not denervated in two mouse models of spinal bulbar muscular atrophy.
Hum Mol Genet. 2016 Sep 1;25(17):3768-3783. doi: 10.1093/hmg/ddw222. Epub 2016 Aug 4.
10
Defects in Neuromuscular Transmission May Underlie Motor Dysfunction in Spinal and Bulbar Muscular Atrophy.
J Neurosci. 2016 May 4;36(18):5094-106. doi: 10.1523/JNEUROSCI.3485-15.2016.

本文引用的文献

1
Peripheral androgen receptor gene suppression rescues disease in mouse models of spinal and bulbar muscular atrophy.
Cell Rep. 2014 May 8;7(3):774-84. doi: 10.1016/j.celrep.2014.02.008. Epub 2014 Apr 16.
3
Antiandrogen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy.
Endocrinology. 2014 Jul;155(7):2624-34. doi: 10.1210/en.2013-1756. Epub 2014 Apr 17.
5
With a little help from my friends: androgens tap BDNF signaling pathways to alter neural circuits.
Neuroscience. 2013 Jun 3;239:124-38. doi: 10.1016/j.neuroscience.2012.12.019. Epub 2012 Dec 20.
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Neurotrophin regulation of neural circuit development and function.
Nat Rev Neurosci. 2013 Jan;14(1):7-23. doi: 10.1038/nrn3379.
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Brain-derived neurotrophic factor and androgen interactions in spinal neuromuscular systems.
Neuroscience. 2013 Jun 3;239:103-14. doi: 10.1016/j.neuroscience.2012.10.028. Epub 2012 Oct 24.
8
Impaired motoneuronal retrograde transport in two models of SBMA implicates two sites of androgen action.
Hum Mol Genet. 2011 Nov 15;20(22):4475-90. doi: 10.1093/hmg/ddr380. Epub 2011 Aug 26.
9
Reduced TrkB expression results in precocious age-like changes in neuromuscular structure, neurotransmission, and muscle function.
J Appl Physiol (1985). 2011 Sep;111(3):844-52. doi: 10.1152/japplphysiol.00070.2011. Epub 2011 Jul 7.
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Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS.
Nat Neurosci. 2010 Nov;13(11):1396-403. doi: 10.1038/nn.2660. Epub 2010 Oct 17.

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