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卵巢癌患者的辐射暴露:不同多层螺旋CT(16层和64层)扫描仪上进行的CT检查的贡献及图像质量评估:一项观察性研究。

Radiation exposure of ovarian cancer patients: contribution of CT examinations performed on different MDCT (16 and 64 slices) scanners and image quality evaluation: an observational study.

作者信息

Rizzo Stefania, Origgi Daniela, Brambilla Sarah, De Maria Federica, Foà Riccardo, Raimondi Sara, Colombo Nicoletta, Bellomi Massimo

机构信息

From the Department of Radiology, European Institute of Oncology, via Ripamonti 435, 20141 Milan (SR, MB), Department of Medical Physics, European Institute of Oncology, via Ripamonti 435, 20141 Milan (DO); Department of Health Sciences, University of Milan, via A.di Rudinì 8, 20142 Milan (SB, FDM, RF, MB); Department of Epidemiology and Biostatistics, European Institute of Oncology, via Ripamonti 435, 20141 Milan (SR); and Department of Gynecology, European Institute of Oncology, via Ripamonti 435, 20141 Milan, Italy (NC).

出版信息

Medicine (Baltimore). 2015 May;94(17):e765. doi: 10.1097/MD.0000000000000765.

Abstract

The objective of this study is to compare radiation doses given to ovarian cancer patients by different computed tomographies (CTs) and to evaluate association between doses and subjective and objective image quality.CT examinations included were performed either on a 16-slice CT, equipped with automatic z-axis tube current modulation, or on a 64-slice CT, equipped with z-axis, xy-axis modulation, and adaptive statistical iterative algorithm (ASIR). Evaluation of dose included the following dose descriptors: volumetric CT dose index (CTDIvol), dose length product (DLP), and effective dose (E). Objective image noise was evaluated in abdominal aorta and liver. Subjective image quality was evaluated by assessment of image noise, spatial resolution and diagnostic acceptability.Mean and median CTDIvol, DLP, and E; correlation between CTDIvol and DLP and patients' weight; comparison of objective noise for the 2 scanners; association between dose descriptors and subjective image quality.The 64-slice CT delivered to patients 24.5% lower dose (P < 0.0001) than 16-slice CT. There was a significant correlation between all dose descriptors (CTDIvol, DLP, E) and weight (P < 0.0001). Objective noise was comparable for the 2 CT scanners. There was a significant correlation between dose descriptors and image noise for the 64-slice CT, and between dose descriptors and spatial resolution for the 16-slice CT.Current dose reduction systems may reduce radiation dose without significantly affecting image quality and diagnostic acceptability of CT exams.

摘要

本研究的目的是比较不同计算机断层扫描(CT)给予卵巢癌患者的辐射剂量,并评估剂量与主观和客观图像质量之间的关联。所纳入的CT检查是在配备自动z轴管电流调制的16层CT上进行的,或者是在配备z轴、xy轴调制以及自适应统计迭代算法(ASIR)的64层CT上进行的。剂量评估包括以下剂量描述符:容积CT剂量指数(CTDIvol)、剂量长度乘积(DLP)和有效剂量(E)。在腹主动脉和肝脏中评估客观图像噪声。通过评估图像噪声、空间分辨率和诊断可接受性来评估主观图像质量。CTDIvol、DLP和E的均值和中位数;CTDIvol与DLP以及患者体重之间的相关性;两台扫描仪的客观噪声比较;剂量描述符与主观图像质量之间的关联。64层CT给予患者的剂量比16层CT低24.5%(P<0.0001)。所有剂量描述符(CTDIvol、DLP、E)与体重之间均存在显著相关性(P<0.0001)。两台CT扫描仪的客观噪声相当。64层CT的剂量描述符与图像噪声之间以及16层CT的剂量描述符与空间分辨率之间存在显著相关性。当前的剂量降低系统可以降低辐射剂量,而不会显著影响CT检查的图像质量和诊断可接受性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6aec/4603053/817387e05fc2/medi-94-e765-g001.jpg

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