al-Salem A H, Khwaja S, Grant C, Dawodu A
Department of Surgery, King Fahad Hospital of the University, Al-Khobar, Saudi Arabia.
J Pediatr Surg. 1989 Dec;24(12):1247-9. doi: 10.1016/s0022-3468(89)80560-3.
Nineteen infants with intrinsic duodenal obstruction are analyzed. Atresia was the most common lesion. An exceptionally high rate of associated anomalies (73.7%) were present; Down's syndrome, the single most common anomaly, was seen in 47% of the infants. In seven infants, the diagnosis was delayed and in another three it was made intraoperatively while establishing a gastrostomy for esophageal atresia. Three infants died without operation because of gross prematurity and multiple anomalies. Of the 16 operated on, three died, one due to peritonitis and the other two because of metabolic derangements. Of the various operative procedures used, no significant difference was found in the final outcome of treatment. A schematic approach to the diagnosis and management is proposed.
对19例先天性十二指肠梗阻患儿进行了分析。闭锁是最常见的病变。合并畸形的发生率异常高（73.7%）；唐氏综合征是最常见的单一畸形，在47%的患儿中可见。7例患儿诊断延迟，另外3例在为食管闭锁行胃造瘘术时术中确诊。3例患儿因严重早产和多发畸形未手术死亡。16例接受手术的患儿中，3例死亡，1例死于腹膜炎，另2例死于代谢紊乱。在所采用的各种手术方法中，治疗的最终结果未发现显著差异。提出了一种诊断和处理的概要方法。
