Gracie D J, Bercik P, Morgan D G, Bolino C, Pintos-Sanchez M I, Moayyedi P, Ford A C
Leeds Gastroenterology Institute, St. James's University Hospital, Leeds, UK.
Leeds Institute of Biomedical and Clinical Sciences, University of Leeds, Leeds, UK.
Neurogastroenterol Motil. 2015 Jul;27(7):1024-31. doi: 10.1111/nmo.12578. Epub 2015 Apr 30.
Psychological factors are associated with functional gastrointestinal (GI) disorders. Literature suggests that somatization is associated with functional dyspepsia (FD). However, the relationship between organic dyspepsia (OD), FD, and FD subtypes and somatization is poorly described. We aimed to examine this issue in a cross-sectional study of secondary care patients.
Demographic and GI symptom data were collected from 4224 adult patients via the Rome III questionnaire. Somatization data were collected using the patient health questionnaire-12. Mean somatization score and number of somatic symptoms were compared between patients with organic and FD, and between FD subtypes using analysis of variance. The same comparison was undertaken for the proportion of patients reporting individual somatic symptoms.
Exactly, 783 patients met criteria for dyspepsia, of whom 231 (29.5%) had organic disease following upper GI endoscopy. Mean somatization scores and number of somatic symptoms were no higher in functional vs OD (p = 0.23; p = 0.19). In addition, while the prevalence of somatization in FD was relatively high, there was no difference in severity of somatization in FD subgroups.
CONCLUSIONS & INFERENCES: Somatization is associated with functional and OD to the same degree. Overall severity of somatization did not appear to vary according to FD subtype.
心理因素与功能性胃肠病(GI)相关。文献表明,躯体化与功能性消化不良(FD)有关。然而,器质性消化不良(OD)、FD及其亚型与躯体化之间的关系鲜有描述。我们旨在通过一项针对二级护理患者的横断面研究来探讨这一问题。
通过罗马III问卷收集了4224名成年患者的人口统计学和胃肠道症状数据。使用患者健康问卷-12收集躯体化数据。采用方差分析比较器质性消化不良患者与FD患者之间以及FD各亚型之间的平均躯体化得分和躯体症状数量。对报告个体躯体症状的患者比例进行了同样的比较。
确切地说,783名患者符合消化不良标准,其中231名(29.5%)在上消化道内镜检查后被诊断为器质性疾病。功能性消化不良患者的平均躯体化得分和躯体症状数量并不高于器质性消化不良患者(p = 0.23;p = 0.19)。此外,虽然FD中躯体化的患病率相对较高,但FD各亚组中躯体化的严重程度并无差异。
躯体化与功能性消化不良和器质性消化不良的关联程度相同。总体而言,躯体化的严重程度似乎不会因FD亚型而异。