Brain-derived neurotrophic factor: a biomarker for obsessive-compulsive disorder?
作者信息
Oliveira-Maia Albino J, Castro-Rodrigues Pedro
机构信息
Champalimaud Neuroscience Programme, Champalimaud Centre for the Unknown Lisboa, Portugal ; Neuropsychiatry Unit, Champalimaud Clinical Centre, Champalimaud Centre for the Unknown Lisboa, Portugal ; Department of Psychiatry and Mental Health, Centro Hospitalar de Lisboa Ocidental Lisboa, Portugal.
Neuropsychiatry Unit, Champalimaud Clinical Centre, Champalimaud Centre for the Unknown Lisboa, Portugal ; Centro Hospitalar Psiquiátrico de Lisboa Lisboa, Portugal.
出版信息
Front Neurosci. 2015 Apr 16;9:134. doi: 10.3389/fnins.2015.00134. eCollection 2015.
Abstract
摘要
相似文献
1
Brain-derived neurotrophic factor: a biomarker for obsessive-compulsive disorder?脑源性神经营养因子：强迫症的生物标志物？
Front Neurosci. 2015 Apr 16;9:134. doi: 10.3389/fnins.2015.00134. eCollection 2015.
2
Brain-derived neurotrophic factor as a biomarker for obsessive-compulsive disorder: A meta-analysis.脑源性神经营养因子作为强迫症的生物标志物：一项荟萃分析。
J Psychiatr Res. 2022 Jul;151:676-682. doi: 10.1016/j.jpsychires.2022.05.026. Epub 2022 May 23.
3
Neurotrophic factors in obsessive-compulsive disorder.强迫症中的神经营养因子。
Psychiatry Res. 2012 Oct 30;199(3):195-200. doi: 10.1016/j.psychres.2012.03.034. Epub 2012 Apr 9.
4
Cytokine, chemokine and BDNF levels in medication-free pediatric patients with obsessive-compulsive disorder.药物治疗的儿童强迫症患者细胞因子、趋化因子和脑源性神经营养因子水平。
Eur Child Adolesc Psychiatry. 2018 Aug;27(8):977-984. doi: 10.1007/s00787-017-1099-3. Epub 2018 Jan 4.
5
The role of the brain-derived neurotrophic factor SNP rs2883187 in the phenotypic expression of obsessive-compulsive disorder.脑源性神经营养因子单核苷酸多态性rs2883187在强迫症表型表达中的作用。
J Clin Neurosci. 2014 May;21(5):790-3. doi: 10.1016/j.jocn.2013.07.037. Epub 2013 Oct 11.
6
Cortisol and Brain-Derived Neurotrophic Factor Levels Prior to Treatment in Children With Obsessive-Compulsive Disorder.强迫症患儿治疗前的皮质醇和脑源性神经营养因子水平
J Clin Psychiatry. 2016 Jul;77(7):e855-9. doi: 10.4088/JCP.15m10146.
7
Is Brain-Derived Neurotrophic Factor (BDNF) Val66Met Polymorphism Associated with Obsessive-Compulsive Disorder? A Meta-Analysis.脑源性神经营养因子（BDNF）Val66Met多态性与强迫症有关吗？一项荟萃分析。
Psychiatr Danub. 2019 Jun;31(2):141-147. doi: 10.24869/psyd.2019.141.
8
Symptom dimensional approach and BDNF in unmedicated obsessive-compulsive patients: an exploratory study.未用药的强迫症患者的症状维度方法与脑源性神经营养因子：一项探索性研究。
CNS Spectr. 2011 Sep;16(9):179-89. doi: 10.1017/S1092852912000363.
9
Brain-derived neurotrophic factor (BDNF) plasma levels in drug-naïve OCD patients are lower than those in healthy people, but are not lower than those in drug-treated OCD patients.药物初治强迫症患者的脑源性神经营养因子（BDNF）血浆水平低于健康人群，但不低于药物治疗的强迫症患者。
J Affect Disord. 2011 Sep;133(1-2):305-10. doi: 10.1016/j.jad.2011.04.002. Epub 2011 May 25.
10
Meta-analysis and association of brain-derived neurotrophic factor (BDNF) gene with obsessive-compulsive disorder.脑源性神经营养因子（BDNF）基因与强迫症的荟萃分析及关联研究
Psychiatr Genet. 2015 Apr;25(2):95-6. doi: 10.1097/YPG.0000000000000077.
引用本文的文献
1
A study of serum brain-derived neurotrophic factor level in individuals with obsessive compulsive disorder and their first-degree relatives as compared to the healthy population.一项关于强迫症患者及其一级亲属与健康人群血清脑源性神经营养因子水平的研究。
Indian J Psychiatry. 2023 Sep;65(9):922-927. doi: 10.4103/indianjpsychiatry.indianjpsychiatry_290_23. Epub 2023 Sep 5.
2
3
OCD-like behavior is caused by dysfunction of thalamo-amygdala circuits and upregulated TrkB/ERK-MAPK signaling as a result of SPRED2 deficiency.强迫症样行为是由丘脑-杏仁核回路的功能障碍以及 SPRED2 缺乏导致的 TrkB/ERK-MAPK 信号转导上调引起的。
Mol Psychiatry. 2018 Feb;23(2):444-458. doi: 10.1038/mp.2016.232. Epub 2017 Jan 10.
本文引用的文献
1
Brain-Derived Neurotrophic Factor (BDNF) protein levels in anxiety disorders: systematic review and meta-regression analysis.焦虑障碍中脑源性神经营养因子（BDNF）蛋白水平：系统评价和荟萃回归分析。
Front Integr Neurosci. 2013 Jul 29;7:55. doi: 10.3389/fnint.2013.00055. eCollection 2013.
2
Neurotrophin regulation of neural circuit development and function.神经营养因子对神经回路发育和功能的调节。
Nat Rev Neurosci. 2013 Jan;14(1):7-23. doi: 10.1038/nrn3379.
3
Sex and stress hormone influences on the expression and activity of brain-derived neurotrophic factor.性和应激激素对脑源性神经营养因子的表达和活性的影响。
Neuroscience. 2013 Jun 3;239:295-303. doi: 10.1016/j.neuroscience.2012.10.073. Epub 2012 Dec 2.
4
Synaptic dysfunction in depression: potential therapeutic targets.抑郁症中的突触功能障碍：潜在的治疗靶点。
Science. 2012 Oct 5;338(6103):68-72. doi: 10.1126/science.1222939.
5
Variant brain-derived neurotrophic factor Val66Met polymorphism alters vulnerability to stress and response to antidepressants.变异脑源性神经营养因子 Val66Met 多态性改变了对压力的易感性和对抗抑郁药的反应。
J Neurosci. 2012 Mar 21;32(12):4092-101. doi: 10.1523/JNEUROSCI.5048-11.2012.
6
Corticosterone reduces brain mitochondrial function and expression of mitofusin, BDNF in depression-like rodents regardless of exercise preconditioning.皮质酮降低抑郁样啮齿动物的大脑线粒体功能和融合蛋白、BDNF 的表达，与运动预处理无关。
Psychoneuroendocrinology. 2012 Jul;37(7):1057-70. doi: 10.1016/j.psyneuen.2011.12.003. Epub 2012 Jan 14.
7
BDNF Val66Met impairs fluoxetine-induced enhancement of adult hippocampus plasticity.脑源性神经营养因子 Val66Met 损害了氟西汀诱导的成年海马体可塑性增强。
Neuropsychopharmacology. 2012 Apr;37(5):1297-304. doi: 10.1038/npp.2011.318. Epub 2012 Jan 4.
8
Fear erasure in mice requires synergy between antidepressant drugs and extinction training.抗抑郁药物和消退训练协同作用才能消除小鼠的恐惧。
Science. 2011 Dec 23;334(6063):1731-4. doi: 10.1126/science.1214592.
9
Brain-derived neurotrophic factor Val66Met allele impairs basal and ketamine-stimulated synaptogenesis in prefrontal cortex.脑源性神经营养因子 Val66Met 等位基因损害前额叶皮质的基础和氯胺酮刺激的突触发生。
Biol Psychiatry. 2012 Jun 1;71(11):996-1005. doi: 10.1016/j.biopsych.2011.09.030. Epub 2011 Oct 29.
10
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses.静息状态下 NMDA 受体阻断可迅速引发抗抑郁行为反应。
Nature. 2011 Jun 15;475(7354):91-5. doi: 10.1038/nature10130.
Zotero 插件