超声造影下前列腺癌的参数：与前列腺癌风险的相关性
Parameters of prostate cancer at contrast-enhanced ultrasound: correlation with prostate cancer risk.
作者信息
Xu Guang, Wu Jian, Yao Ming-Hua, Yao Xu-Dong, Peng Bo, Wei Qing, Xu Hui-Xiong, Wu Rong
机构信息
Department of Medical Ultrasound, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
Department of Urology, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China.
出版信息
Int J Clin Exp Med. 2015 Feb 15;8(2):2562-9. eCollection 2015.
OBJECTIVE
to investigate the correlation between the parameters of prostate cancer (PCa) at contrast-enhanced ultrasound (CEUS) with PCa risk.
METHODS
84 patients (68 ± 8 years; range, 33-79 years) who had undergone CEUS were included. All the images were offline analyzed. Parameters (maximum intensity (IMAX), rise time (RT), time to peak (TTP) and mean transit time (mTT)) were recorded and compared with PSA level, Gleason score, clinical stages and PCa risk.
RESULTS
Age was correlated significantly with PCa risk. RT and mTT of outer gland were associated with PCa risk. No significant correlation was found between PSA and CEUS enhancement parameters. Furthermore, with the exception of IMAX of inner gland and IMAX of outer gland, there were no significant differences of enhancement parameters in Gleason score groups and clinical stages groups.
CONCLUSION
The enhancement parameters of PCa at CEUS may be used to predict PCa risk. And it is helpful for the choice of therapeutic options.
目的
探讨前列腺癌（PCa）在超声造影（CEUS）下的参数与PCa风险之间的相关性。
方法
纳入84例行CEUS检查的患者（年龄68±8岁；范围33 - 79岁）。所有图像均进行离线分析。记录参数（最大强度（IMAX）、上升时间（RT）、达峰时间（TTP）和平均通过时间（mTT）），并与前列腺特异性抗原（PSA）水平、 Gleason评分、临床分期及PCa风险进行比较。
结果
年龄与PCa风险显著相关。外腺的RT和mTT与PCa风险相关。PSA与CEUS增强参数之间未发现显著相关性。此外，除内腺IMAX和外腺IMAX外，Gleason评分组和临床分期组的增强参数无显著差异。
结论
CEUS下PCa的增强参数可用于预测PCa风险。这有助于治疗方案的选择。
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