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子宫动脉化疗栓塞术在治疗剖宫产瘢痕妊娠中的应用

An application of uterine artery chemoembolization in treating cesarean scar pregnancy.

作者信息

Huang Yan, Li Youfei, Xi Rongkai, Chen Zhengqiong, Ying Demei, Li Zhen, Yang Ying

机构信息

Department of Obstetrics and Gynecology, Xin Qiao Hospital, Third Military Medical University Chongqing, China.

出版信息

Int J Clin Exp Med. 2015 Feb 15;8(2):2570-7. eCollection 2015.

Abstract

OBJECTIVE

To discuss the feasibility and safety of uterine artery chemoembolization in treating cesarean scar pregnancy (CSP).

METHODS

During the period between 1(st) of May 2009 and 17(th) of January 2014, uterine artery chemoembolization with methotrexate (MTX) and gelatin sponge was performed in 31 patients diagnosed with CSP in Xinqiao Hospital. Curettage of uterus was carried out within 24-48 hours after the procedure.

RESULTS

The success rate of bilateral uterine artery chemoembolization was 100%. The mean blood loss during curettage procedure was only 8.32±4.76 (2-20) ml. The mean time for serum β-HCG normalization was 33.81±17.47 (15-82) days, and the mean time for gestational sacs elimination was 29.52±20.93 (4-90) days. The mean time of hospital stay was 5.10±1.08 (4-8) days.

CONCLUSIONS

No serious complications occurred. The uterine artery chemoembolization is an effective and safe treatment for CSP, which greatly reduces the necessity of hysterectomy.

摘要

目的

探讨子宫动脉化疗栓塞术治疗剖宫产瘢痕妊娠(CSP)的可行性及安全性。

方法

2009年5月1日至2014年1月17日期间,新桥医院对31例诊断为CSP的患者采用甲氨蝶呤(MTX)联合明胶海绵行子宫动脉化疗栓塞术。术后24 - 48小时内行刮宫术。

结果

双侧子宫动脉化疗栓塞术成功率为100%。刮宫术中平均出血量仅为8.32±4.76(2 - 20)ml。血清β-HCG恢复正常的平均时间为33.81±17.47(15 - 82)天,孕囊消失的平均时间为29.52±20.93(4 - 90)天。平均住院时间为5.10±1.08(4 - 8)天。

结论

未发生严重并发症。子宫动脉化疗栓塞术是治疗CSP的一种有效且安全的方法,极大地降低了子宫切除术的必要性。

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