Obstetrics Department, Women's Hospital, School of Medicine, Zhejiang University, Zhejiang, People's Republic of China.
Acta Obstet Gynecol Scand. 2010 Dec;89(12):1592-4. doi: 10.3109/00016349.2010.512973. Epub 2010 Aug 23.
We have evaluated the efficacy of methotrexate-based bilateral uterine arterial chemoembolization for treating cesarean scar pregnancy (CSP) in 52 women between January 2005 and December 2009. Ten patients experienced massive vaginal hemorrhage after a misdiagnosis and subsequent curettage. Bleeding in these patients was reduced after chemoembolization. Dilation and curettage was not done in five of these patients because ultrasound scanning showed sparse or no blood flow in the previous gestational sac area. The five remaining patients, along with additional 42 patients who were diagnosed with CSP, underwent ultrasound-guided dilation and curettage within 24-48 hours following chemoembolization. Patients tolerated the procedure well and only mild bleeding occurred. The positive clinical outcomes in these patients support the use of bilateral uterine artery chemoembolization for the treatment of CSP.
我们评估了甲氨蝶呤联合双侧子宫动脉化疗栓塞治疗剖宫产术后子宫瘢痕妊娠（CSP）的疗效，该研究共纳入 52 例 2005 年 1 月至 2009 年 12 月间的患者。10 例患者在误诊并随后刮宫后出现大出血，这些患者在化疗栓塞后出血减少。其中 5 例患者因超声检查显示原妊娠囊区血流稀疏或无血流而未行刮宫术。其余 5 例患者与另外 42 例 CSP 患者在化疗栓塞后 24-48 小时内行超声引导下刮宫术。患者均能耐受该操作，仅发生轻微出血。这些患者的良好临床结局支持使用双侧子宫动脉化疗栓塞治疗 CSP。
