Humayun Mohammad, Haider Iqbal, Badshah Aliena, Subhan Fazle
Department of Medicine, Medical C Unit, Khyber Teaching Hospital, Peshawar.
J Coll Physicians Surg Pak. 2015 Apr;25 Suppl 1:S66-8.
A 15-year-old boy was referred to the hospital from the periphery with a history of ingestion of 5 wheat pills (aluminium phosphide) 5 days back. He had been given a stomach wash in his village hospital prior to referral. On arrival, he was jaundiced and had developed haematuria too, but otherwise appeared well in himself. Four days after admission, his haemoglobin showed a marked drop and he was shifted to intensive care, keeping in mind the high mortality rate associated with aluminium phosphide intoxication. His G6PD levels were checked, and he turned out to be G6PD deficient. The patient was given intravenous magnesium sulphate and supportive care and he improved subsequently. Wheat pill poisoning carries a high mortality of 98% in some cases; despite the high mortality, this patient survived. This may mean that G6PD deficiency has a protective role in poisoning due to aluminium phosphide.
一名15岁男孩5天前从周边地区被转诊至本院，有摄入5粒小麦丸（磷化铝）的病史。转诊前他在当地医院接受了洗胃。入院时，他出现黄疸，也出现了血尿，但除此之外他自身状况看起来尚可。入院4天后，他的血红蛋白显著下降，鉴于磷化铝中毒相关的高死亡率，他被转入重症监护室。检查了他的葡萄糖-6-磷酸脱氢酶（G6PD）水平，结果发现他G6PD缺乏。该患者接受了静脉注射硫酸镁及支持治疗，随后病情好转。小麦丸中毒在某些情况下死亡率高达98%；尽管死亡率很高，但该患者存活了下来。这可能意味着G6PD缺乏在磷化铝中毒中具有保护作用。
