de Souza Marcio Leandro Ribeiro, Jansen Ann Kristine, Martins Aline Stangherlin, Rodrigues Luiz Oswaldo Carneiro, de Rezende Nilton Alves
Federal University of Minas Gerais, Brazil.
Federal University of Minas Gerais, Brazil.
Nutrition. 2015 Jun;31(6):858-62. doi: 10.1016/j.nut.2014.12.021. Epub 2014 Dec 31.
To evaluate nutrient intake among adult neurofibromatosis type 1 (NF1) patients.
A cross-sectional study of 60 NF1 patients (29 men, 31 women) who were ≥18 y old and were evaluated from September 2012 to September 2013 in a neurofibromatosis outpatient reference center. Patients underwent nutritional assessment, including anthropometric and dietary data collection. Food intake was evaluated using three, non-consecutive, self-reported 24-h dietary recall surveys, and nutrient intake was analyzed according to the recommendations of the dietary reference intake document.
Forty-three patients (72%) recorded energy consumption lower than the estimated daily energy requirement (EER). Men (25/29, 86.2%) were more likely to fail to meet their target EER, compared to women (18/31, 58.1%) (P = 0.016). Inadequate intake of vitamin D, magnesium, calcium, and pyridoxine was noted between men and women, and all patients consumed excess sodium. NF1 patients did not consume adequate amounts of fiber or vitamins A and C. Excessive consumption of saturated fatty acids and lipids was also observed in both male and female patients.
In this study, NF1 patients consumed an unhealthy diet that was rich in fats and sodium and lacking in fiber, vitamins, and minerals. Further studies are needed to investigate the role of these dietary and nutritional patterns in the severity of the clinical manifestations of NF1.
评估成年1型神经纤维瘤病（NF1）患者的营养摄入情况。
对60例NF1患者（29例男性，31例女性）进行横断面研究，这些患者年龄≥18岁，于2012年9月至2013年9月在一家神经纤维瘤病门诊参考中心接受评估。患者接受了营养评估，包括人体测量和饮食数据收集。通过三次非连续的、自我报告的24小时饮食回顾调查来评估食物摄入量，并根据膳食参考摄入量文件的建议分析营养摄入量。
43例患者（72%）记录的能量消耗低于估计的每日能量需求（EER）。与女性（18/31，58.1%）相比，男性（25/29，86.2%）更有可能未达到其目标EER（P = 0.016）。男性和女性均存在维生素D、镁、钙和吡哆醇摄入不足的情况，所有患者的钠摄入量均超标。NF1患者未摄入足够量的纤维、维生素A和维生素C。男性和女性患者均存在饱和脂肪酸和脂质摄入过多的情况。
在本研究中，NF1患者的饮食不健康，富含脂肪和钠，缺乏纤维、维生素和矿物质。需要进一步研究来调查这些饮食和营养模式在NF1临床表现严重程度中的作用。
