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[搏动灌注对主动脉冠状动脉搭桥术的影响]

[The effect of pulsatile perfusion on aortocoronary bypass grafting].

作者信息

Gohra H, Kaneda Y, Furukawa S, Oda T, Miyamoto M, Mori F, Esato K

出版信息

Kyobu Geka. 1989 Nov;42(12):974-9; discussion 979-81.

PMID:2593408
Abstract

To evaluate the effect of pulsatile perfusion on myocardial protection and peripheral circulation, 23 patients undergoing aortocoronary bypass grafting were studied by dividing two groups; one with pulsatile perfusion technique (11 patients) and the other with non-pulsatile (12 patients). The cardiac functional assessments were made on CI, LVSWI, PCWP, CVP at 3, 6, 12 and 24 hours after the operation and the enzyme (CPK, CPK-MB, LDH, GOT) sampling were performed on 1, 2, 4 and 7 days after the operation. The difference between esophageal and rectal temperature, and urine output during cardiopulmonary bypass, indicating the peripheral circulation, were also measured. From these clinical results, it is concluded that pulsatile perfusion method is to be beneficial in myocardial protection and peripheral circulation during operation of aortocoronary bypass grafting.

摘要

为评估搏动灌注对心肌保护和外周循环的影响,将23例行主动脉冠状动脉搭桥术的患者分为两组进行研究;一组采用搏动灌注技术(11例患者),另一组采用非搏动灌注(12例患者)。术后3、6、12和24小时对心脏功能进行心指数(CI)、左室每搏作功指数(LVSWI)、肺毛细血管楔压(PCWP)、中心静脉压(CVP)评估,并在术后1、2、4和7天进行酶(肌酸磷酸激酶(CPK)、肌酸磷酸激酶同工酶(CPK-MB)、乳酸脱氢酶(LDH)、谷草转氨酶(GOT))采样。还测量了体外循环期间食管温度与直肠温度之差以及尿量,以反映外周循环情况。从这些临床结果得出结论,搏动灌注法在主动脉冠状动脉搭桥术手术过程中对心肌保护和外周循环有益。

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