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影响医生预防静脉曲张出血决策的因素。

Factors impacting physicians' decisions to prevent variceal hemorrhage.

作者信息

Yan Kathleen, Bridges John F P, Augustin Salvador, Laine Loren, Garcia-Tsao Guadalupe, Fraenkel Liana

机构信息

Section of Rheumatology, Yale University School of Medicine, 300 Cedar ST, TAC Bldg, RM #525, P.O. Box 208031, New Haven, CT, USA.

Yale University School of Medicine, New Haven, Connecticut and VA Connecticut Health Care System, West Haven, CT, USA.

出版信息

BMC Gastroenterol. 2015 May 2;15:55. doi: 10.1186/s12876-015-0287-1.

Abstract

BACKGROUND

Reasons underlying the variability of physicians' preferences for non-selective beta-blockers (BBs) and endoscopic variceal ligation (EVL) to prevent a first variceal bleed have not been empirically studied. Our aims were to examine whether 1) gastroenterologists can be classified into distinct subgroups based on how they prioritize specific treatment attributes and 2) physician characteristics are associated with treatment preference.

METHODS

We surveyed physicians to determine their preferred treatment for a standardized patient with large varices and examined the influence of treatment characteristics on physicians' decision making using best-worst scaling. Latent class analysis was used to examine whether physicians could be classified into groups with similar decision-making styles.

RESULTS

110 physicians were interviewed (participation rate 39%). The majority spent two or more days a week performing endoscopies and had practices comprising less than 25% of patients with liver disease. Latent class analysis demonstrated that physicians could be classified into at least two distinct groups. Most (n = 80, Group 1) were influenced solely by the ability to visually confirm eradication of varices. In contrast, members of Group 2 (n = 30) were influenced by the side effects and mechanism of action of BBs. Group 1 members were more likely to have practices that included fewer patients with liver disease and more likely to choose options including EVL (p = 0.01 for both).

CONCLUSIONS

Among physicians, where the majority performs endoscopy on two or more days per week, most prefer prevention strategies which include EVL. This may be due to the strong appeal of being able to visualize eradication of varices.

摘要

背景

医生对于使用非选择性β受体阻滞剂(BBs)和内镜下静脉曲张结扎术(EVL)预防首次静脉曲张出血的偏好存在差异,其背后原因尚未得到实证研究。我们的目的是检验:1)胃肠病学家是否可根据他们对特定治疗属性的优先排序分为不同亚组;2)医生特征是否与治疗偏好相关。

方法

我们对医生进行调查,以确定他们对一名患有大静脉曲张的标准化患者的首选治疗方法,并使用最佳-最差标度法研究治疗特征对医生决策的影响。采用潜在类别分析来检验医生是否可分为具有相似决策风格的组。

结果

共访谈了110名医生(参与率39%)。大多数医生每周花两天或更多时间进行内镜检查,其诊疗业务中肝病患者占比不到25%。潜在类别分析表明,医生可分为至少两个不同的组。大多数(n = 80,第1组)仅受静脉曲张可视性根除能力的影响。相比之下,第2组(n = 30)的成员受BBs的副作用和作用机制影响。第1组成员的诊疗业务中肝病患者较少,且更有可能选择包括EVL的方案(两者p值均为0.01)。

结论

在大多数每周进行两天或更多天内镜检查的医生中,大多数更喜欢包括EVL的预防策略。这可能是由于能够直观看到静脉曲张根除具有很大吸引力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5605/4423490/ad0b353deae9/12876_2015_287_Fig1_HTML.jpg

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