Chen Stephanie H, Grandhi Ramesh, Deibert Christopher P, Jovin Tudor G, Gardner Paul A, Ducruet Andrew F
University of Pittsburgh School of Medicine, Pittsburgh, USA.
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, USA.
Interv Neuroradiol. 2015 Apr;21(2):184-7. doi: 10.1177/1591019915581990. Epub 2015 May 1.
Complications associated with intra-arterial infusion of vasodilator agents for the treatment of vasospasm associated with a ruptured cerebral aneurysm are extremely rare. We present the case of a patient who developed left lower extremity monoplegia following intra-arterial infusion of verapamil for treatment of diffuse cerebral vasospasm, 6 days after initially undergoing treatment of a ruptured right A1-2 junction aneurysm. A repeat angiogram following this intra-arterial vasodilator treatment demonstrated a coil loop which had herniated into the right A2 artery. Herein, we describe a previously unreported complication which occurred following intra-arterial pharmacologic vasospasm treatment, review the existing literature, and suggest potential causes and treatment options.
与动脉内输注血管扩张剂治疗破裂性脑动脉瘤相关的血管痉挛相关并发症极为罕见。我们报告一例患者,在最初接受右侧A1-2交界处动脉瘤治疗6天后,动脉内输注维拉帕米治疗弥漫性脑血管痉挛后出现左下肢单瘫。此次动脉内血管扩张剂治疗后复查血管造影显示一个弹簧圈疝入右侧A2动脉。在此,我们描述动脉内药物性血管痉挛治疗后发生的一种此前未报告的并发症,回顾现有文献,并提出潜在原因和治疗选择。