一例妊娠期双侧嗜铬细胞瘤病例。
A case of bilateral pheochromocytoma during pregnancy.
作者信息
Kitayama Kishu, Kashiwagi Shinichiro, Amano Ryosuke, Noda Satoru, Ohira Go, Yamazoe Sadaaki, Kimura Kenjiro, Hamamoto Kae, Hamuro Akihiro, Ohsawa Masahiko, Onoda Naoyoshi, Hirakawa Kosei
机构信息
Department of Surgical Oncology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, Japan.
Department of Metabolism and Molecular Medicine, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, Japan.
出版信息
BMC Surg. 2015 May 3;15:55. doi: 10.1186/s12893-015-0041-1.
BACKGROUND
Pheochromocytoma is a disease where catecholamines are secreted. If pheochromocytoma occurs during pregnancy, it can be difficult to diagnose because it is similar to pregnancy-induced hypertension. Furthermore, bilateral pheochromocytoma during pregnancy is even rarer than unilateral pheochromocytoma.
CASE PRESENTATION
A 32-year-old primigravida, who was 12 weeks' pregnant, was aware of right abdominal discomfort. Masses in both adrenal glands were observed by abdominal ultrasonography. She was diagnosed with pheochromocytoma. Bilateral adrenalectomy was undertaken at 15 weeks' gestation and she continued pregnancy. At 39 weeks' gestation, a healthy male neonate was delivered. She was discharged on the 4th postpartum day.
CONCLUSIONS
We present a case of bilateral pheochromocytoma during pregnancy that was diagnosed in the first trimester. Differentiating pheochromocytoma from pregnancy-induced hypertension is important. Early diagnosis and appropriate blood pressure management with medical treatment followed by surgical removal of the tumor results in good maternal and fetal outcomes.
背景
嗜铬细胞瘤是一种分泌儿茶酚胺的疾病。如果嗜铬细胞瘤在孕期发生，由于其与妊娠期高血压相似，可能难以诊断。此外，孕期双侧嗜铬细胞瘤比单侧嗜铬细胞瘤更为罕见。
病例介绍
一名32岁初产妇，孕12周，自觉右腹不适。腹部超声检查发现双侧肾上腺有肿块。她被诊断为嗜铬细胞瘤。在孕15周时进行了双侧肾上腺切除术，之后继续妊娠。孕39周时，分娩出一名健康男婴。她在产后第4天出院。
结论
我们报告了一例在孕早期被诊断出的孕期双侧嗜铬细胞瘤病例。区分嗜铬细胞瘤与妊娠期高血压很重要。早期诊断并通过药物进行适当的血压管理，随后手术切除肿瘤，可带来良好的母婴结局。
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