Ducarme Guillaume, Chesnoy Veronique, Lemarié Philippe, Koumaré Sekou, Krawczykowski Daniel
Department of Obstetrics and Gynecology, Centre Hospitalier Departemental, La Roche sur Yon, France.
Medical Records Department, Centre Hospitalier Departemental, La Roche sur Yon, France.
Int J Gynaecol Obstet. 2015 Aug;130(2):127-31. doi: 10.1016/j.ijgo.2015.03.022. Epub 2015 Apr 24.
To analyze pregnancy outcomes after laparoscopic sleeve gastrectomy (LSG) according to body mass index (BMI) at conception and the interval between LSG and pregnancy.
In a retrospective study, data were obtained for all women who became pregnant after LSG at a center in France between December 2001 and December 2011. Frequencies of perinatal events according to BMI at conception and the interval between LSG and pregnancy were compared.
A total of 63 pregnancies occurring in 54 patients were included, among which 52 (83%) occurred after the first postoperative year and 26 (41%) in women who remained obese. Compared with women who were no longer obese at conception, women who were still obese delivered neonates of significantly lower gestational age at birth (P=0.02) and birth weight (P=0.001). Odds of preterm delivery were also increased (odds ratio 4.37, 95% confidence interval 1.17-16.27; P=0.03). Maternal and neonatal outcomes according to the interval between LSG and pregnancy did not differ significantly.
Women who remain obese following LSG are at increased risk of adverse outcomes, including low gestational age at birth, low birth weight, and preterm delivery, and should be regarded as a risk group.
根据受孕时的体重指数(BMI)以及腹腔镜袖状胃切除术(LSG)与怀孕之间的间隔时间,分析腹腔镜袖状胃切除术后的妊娠结局。
在一项回顾性研究中,获取了2001年12月至2011年12月期间在法国某中心接受LSG术后怀孕的所有女性的数据。比较了根据受孕时BMI以及LSG与怀孕之间的间隔时间的围产期事件发生率。
共纳入了54例患者的63次妊娠,其中52次(83%)发生在术后第一年,26次(41%)发生在仍肥胖的女性中。与受孕时不再肥胖的女性相比,仍肥胖的女性分娩的新生儿出生时孕周明显更低(P=0.02),出生体重也更低(P=0.001)。早产几率也增加了(优势比4.37,95%置信区间1.17 - 16.27;P=0.03)。根据LSG与怀孕之间的间隔时间得出的母婴结局无显著差异。
LSG术后仍肥胖的女性出现不良结局的风险增加,包括出生孕周低、出生体重低和早产,应被视为高危人群。