Napeñas Joel J, Kujan Omar, Arduino Paolo G, Sukumar Suma, Galvin Sheila, Baričević Marinka, Costella John, Czerninski Rakefet, Peterson Douglas E, Lockhart Peter B
Division of Oral Medicine and Radiology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Department of Oral Medicine, Carolinas Medical Center, Charlotte, North Carolina, USA.
Oral and Maxillofacial Sciences Department, Al-Farabi College for Dentistry and Nursing, Riyadh, Kingdom of Saudi Arabia; Oral Pathology and Medicine Department, Faculty of Dentistry, Hama University, Hama, Syria.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Aug;120(2):207-26. doi: 10.1016/j.oooo.2015.03.001. Epub 2015 Mar 11.
Current recommendations for safe and effective dental management are less than optimal for some medical conditions because of limited evidence, conflicting conclusions, or both. This review (1) compiled and evaluated dental management recommendations for select medical conditions; (2) summarized recommendations and their assigned levels of evidence; (3) identified areas of conflict, ambiguity, or both; and (4) identified issues that warrant future research, enhanced consensus statements, or both.
Systematic literature searches were performed for guideline publications, systematic and narrative reviews, and opinion documents containing recommendations for (1) medication-related osteonecrosis of the jaw (MRONJ); (2) cardiovascular diseases (CVDs); (3) prosthetic joints (PJs); and (4) systemic steroid therapy (SST).
The search yielded the following numbers of publications that met the inclusion criteria: MRONJ - 116; CVDs - 54; prosthetic joints - 39; and systemic steroids - 12.
Very few of the compiled recommendations were assigned or linked to levels of evidence by their authors. Key conclusions include the following: MRONJ-expert recommendations trend toward proceeding with dental treatment with little to no modification in osteoporotic patients on bisphosphonates; CVDs-current recommendations are primarily directed to general surgery and applied to dentistry; PJs-routine antibiotic prophylaxis is not indicated for dental treatment; and SST-steroid supplementation is not indicated for most patients undergoing dental procedures under local anesthesia.
由于证据有限、结论相互矛盾或两者皆有,目前关于安全有效的牙科治疗管理的建议对某些医疗状况而言并非最佳。本综述(1)汇编并评估了针对特定医疗状况的牙科治疗管理建议;(2)总结了这些建议及其指定的证据级别;(3)确定了存在冲突、模糊或两者皆有的领域;(4)确定了需要未来研究、加强共识声明或两者皆需的问题。
对指南出版物、系统综述和叙述性综述以及包含以下方面建议的意见文件进行了系统的文献检索:(1)药物相关性颌骨坏死(MRONJ);(2)心血管疾病(CVD);(3)人工关节(PJ);(4)全身类固醇治疗(SST)。
检索得到符合纳入标准的出版物数量如下:MRONJ - 116篇;CVD - 54篇;人工关节 - 39篇;全身类固醇 - 12篇。
所汇编的建议中,极少有作者为其指定或关联证据级别。主要结论如下:MRONJ - 专家建议倾向于在使用双膦酸盐的骨质疏松患者中,对牙科治疗进行极少或不做调整;CVD - 当前建议主要针对普通外科手术,应用于牙科领域;PJ - 牙科治疗无需常规预防性使用抗生素;SST - 大多数在局部麻醉下接受牙科手术的患者无需补充类固醇。