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2003 - 2012年威斯康星州海洛因过量用药的趋势与特征

Trends and characteristics of heroin overdoses in Wisconsin, 2003-2012.

作者信息

Meiman Jon, Tomasallo Carrie, Paulozzi Leonard

机构信息

Epidemic Intelligence Service, Centers for Disease Control and Prevention, Wisconsin Division of Public Health, 1 West Wilson Street, Room 150, Madison, WI 53703, United States.

Wisconsin Division of Public Health, 1 West Wilson Street, Room 150, Madison, WI 53703, United States.

出版信息

Drug Alcohol Depend. 2015 Jul 1;152:177-84. doi: 10.1016/j.drugalcdep.2015.04.002. Epub 2015 Apr 18.

Abstract

BACKGROUND

Heroin abuse has increased substantially during the past decade in the United States. This study describes trends and demographic shifts of heroin overdoses and heroin-related fatalities in Wisconsin and contrasts these with prescription opioid overdoses.

METHODS

This study was cross-sectional using databases of emergency department (ED) visits, hospital admissions, and death certificates in Wisconsin, United States, during 2003-2012. Cases were Wisconsin residents treated for heroin or prescription opioid overdose, and residents who died of heroin-related drug poisoning. Primary measurements were rates over time and by geographic region, and rates and rate ratios for selected demographic characteristics.

RESULTS

During 2003-2012, age-adjusted rates of heroin overdoses treated in EDs increased from 1.0 to 7.9/100,000 persons; hospitalized heroin overdoses increased from 0.7 to 3.5/100,000. Whites accounted for 68% of hospitalized heroin overdoses during 2003-2007 but 80% during 2008-2012. Heroin-related deaths were predominantly among urban residents; however, rural fatalities accounted for zero deaths in 2003 but 31 (17%) deaths in 2012. Among patients aged 18-34 years, those hospitalized with heroin overdose were more often men (73.0% versus 54.9%), uninsured (44.2% versus 29.9%), and urban (84.3% versus 73.2%) than those with prescription opioid overdose. Rates of ED visits for heroin overdose in this age group exceeded rates for prescription opioid overdose in 2012 (26.1/100,000 versus 12.6/100,000 persons, respectively).

CONCLUSIONS

An epidemic of heroin abuse is characterized by demographic shifts toward whites and rural residents. Rates of heroin overdose in younger persons now exceed rates of prescription opioid overdose.

摘要

背景

在过去十年中,美国海洛因滥用现象大幅增加。本研究描述了威斯康星州海洛因过量使用及与海洛因相关的死亡情况的趋势和人口结构变化,并将这些情况与处方阿片类药物过量使用情况进行对比。

方法

本研究为横断面研究,使用了2003年至2012年期间美国威斯康星州急诊科就诊、医院入院和死亡证明的数据库。病例为接受海洛因或处方阿片类药物过量治疗的威斯康星州居民,以及死于海洛因相关药物中毒的居民。主要测量指标为随时间和地理区域变化的发生率,以及选定人口特征的发生率和率比。

结果

在2003年至2012年期间,急诊科治疗的海洛因过量使用的年龄调整发生率从每10万人1.0例增至7.9例;住院海洛因过量使用发生率从每10万人0.7例增至3.5例。2003年至2007年期间,白人占住院海洛因过量使用病例的68%,但在2008年至2012年期间占80%。与海洛因相关的死亡主要发生在城市居民中;然而,农村地区的死亡人数在2003年为零,但在2012年为31例(占17%)。在18至34岁的患者中,因海洛因过量住院的患者比因处方阿片类药物过量住院的患者更常为男性(分别为73.0%和54.9%)、未参保者(分别为44.2%和29.9%)以及城市居民(分别为84.3%和73.2%)。2012年,该年龄组海洛因过量的急诊科就诊率超过了处方阿片类药物过量的就诊率(分别为每10万人26.1例和12.6例)。

结论

海洛因滥用的流行表现为人口结构向白人和农村居民转变。现在年轻人中海洛因过量的发生率超过了处方阿片类药物过量的发生率。

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