Department of Medicine, University of Colorado, Aurora, Colorado, USA.
Department of Cardiology, Veterans Affairs Eastern Colorado Health Care System, Denver, Colorado, USA Division of Cardiovascular Medicine, Department of Medicine, University of Colorado, Denver, Colorado, USA.
Heart. 2015 Jul;101(14):1097-102. doi: 10.1136/heartjnl-2015-307588. Epub 2015 May 2.
Atrial fibrillation (AF) is a very common arrhythmia and significantly increases stroke risk. This risk can be mitigated with oral anticoagulation, but AF is often asymptomatic, or occult, preventing timely detection and treatment. Accordingly, occult AF may cause stroke before it is clinically diagnosed. Currently, guidelines for the early detection and treatment of occult AF are limited. This review addresses recent advancements in occult AF detection methods, identification of populations at high risk for occult AF, the treatment of occult AF with oral anticoagulation, as well as ongoing trials that may answer critically important questions regarding occult AF screening.
心房颤动（AF）是一种非常常见的心律失常，显著增加了中风的风险。口服抗凝剂可以降低这种风险，但 AF 常常无症状，或隐匿性，从而无法及时发现和治疗。因此，隐匿性 AF 可能在临床上诊断之前导致中风。目前，隐匿性 AF 的早期检测和治疗指南有限。本综述讨论了隐匿性 AF 检测方法的最新进展、隐匿性 AF 高危人群的识别、口服抗凝剂治疗隐匿性 AF 以及正在进行的试验，这些试验可能会回答关于隐匿性 AF 筛查的重要问题。
