Gooneratne Alena Talia, James Alexander Owen, Gupta Jyoti, Abdulaal Yasser
Maidstone and Tunbridge Wells NHS Trust, Maidstone, UK.
Tunbridge Wells Hospital, Tunbridge Wells, UK.
BMJ Case Rep. 2015 May 2;2015:bcr2014208472. doi: 10.1136/bcr-2014-208472.
We discuss a rare presentation of malignant teratoma in a 63-year-old woman who was admitted to accident and emergency with abdominal distension, bloody diarrhoea and peritonitis. CT of the abdomen and pelvis showed free air in the abdomen and a gas-fluid filled cavity measuring 12×6 cm in the mid-pelvis with possible fistulation that was suspicious for malignancy. A 10×12 cm ruptured dermoid cyst was found intraoperatively, which was adherent to the bowel wall. Bulky lymph nodes were also appreciated. The surgeon suspected a metastatic malignant teratoma, and a Hartmann's procedure, total abdominal hysterectomy and bilateral salpingoopherectomy were performed with clearance of the para-aortic lymph nodes. Subsequent histological analysis revealed a squamous cell carcinoma arising from an ovarian malignant teratoma. The patient went on to have carboplatin and paclitaxel chemotherapy and is alive at 6 months follow-up.
我们讨论了一名63岁女性罕见的恶性畸胎瘤病例,该患者因腹胀、血性腹泻和腹膜炎入住急诊。腹部和盆腔CT显示腹腔内有游离气体,盆腔中部有一个12×6厘米的气液腔,可能存在瘘管,怀疑为恶性病变。术中发现一个10×12厘米的破裂皮样囊肿,与肠壁粘连。还发现了肿大的淋巴结。外科医生怀疑是转移性恶性畸胎瘤,遂进行了哈特曼手术、全腹子宫切除术和双侧输卵管卵巢切除术,并清扫了腹主动脉旁淋巴结。随后的组织学分析显示,卵巢恶性畸胎瘤发生了鳞状细胞癌。该患者接受了卡铂和紫杉醇化疗,随访6个月时仍存活。