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成熟囊性畸胎瘤中发生的鳞状细胞癌侵犯乙状结肠:一种罕见的表现。

Squamous cell carcinoma arising in a mature cystic teratoma invading the sigmoid colon: a rare presentation.

作者信息

Gooneratne Alena Talia, James Alexander Owen, Gupta Jyoti, Abdulaal Yasser

机构信息

Maidstone and Tunbridge Wells NHS Trust, Maidstone, UK.

Tunbridge Wells Hospital, Tunbridge Wells, UK.

出版信息

BMJ Case Rep. 2015 May 2;2015:bcr2014208472. doi: 10.1136/bcr-2014-208472.

Abstract

We discuss a rare presentation of malignant teratoma in a 63-year-old woman who was admitted to accident and emergency with abdominal distension, bloody diarrhoea and peritonitis. CT of the abdomen and pelvis showed free air in the abdomen and a gas-fluid filled cavity measuring 12×6 cm in the mid-pelvis with possible fistulation that was suspicious for malignancy. A 10×12 cm ruptured dermoid cyst was found intraoperatively, which was adherent to the bowel wall. Bulky lymph nodes were also appreciated. The surgeon suspected a metastatic malignant teratoma, and a Hartmann's procedure, total abdominal hysterectomy and bilateral salpingoopherectomy were performed with clearance of the para-aortic lymph nodes. Subsequent histological analysis revealed a squamous cell carcinoma arising from an ovarian malignant teratoma. The patient went on to have carboplatin and paclitaxel chemotherapy and is alive at 6 months follow-up.

摘要

我们讨论了一名63岁女性罕见的恶性畸胎瘤病例,该患者因腹胀、血性腹泻和腹膜炎入住急诊。腹部和盆腔CT显示腹腔内有游离气体,盆腔中部有一个12×6厘米的气液腔,可能存在瘘管,怀疑为恶性病变。术中发现一个10×12厘米的破裂皮样囊肿,与肠壁粘连。还发现了肿大的淋巴结。外科医生怀疑是转移性恶性畸胎瘤,遂进行了哈特曼手术、全腹子宫切除术和双侧输卵管卵巢切除术,并清扫了腹主动脉旁淋巴结。随后的组织学分析显示,卵巢恶性畸胎瘤发生了鳞状细胞癌。该患者接受了卡铂和紫杉醇化疗,随访6个月时仍存活。

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本文引用的文献

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Malignant transformation of a mature cystic teratoma of the ovary with rupture.卵巢成熟囊性畸胎瘤破裂恶变。
Jpn J Radiol. 2010 Jun;28(5):372-5. doi: 10.1007/s11604-010-0434-0. Epub 2010 Jun 30.
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Diagnosis of squamous cell carcinoma arising from mature cystic teratoma of the ovary.卵巢成熟性囊性畸胎瘤恶变鳞癌的诊断
Cancer. 1998 Jun 1;82(11):2249-55. doi: 10.1002/(sici)1097-0142(19980601)82:11<2249::aid-cncr21>3.0.co;2-t.

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