Shanthala P R, Saldhana Prema, Upadhyaya Krishnaraj
J Indian Med Assoc. 2014 Feb;112(2):128, 130.
Gynandroblastoma is a rare ovarian mixed sex cord stromal tumour with very few cases reported in literature. These tumours are considered to be potentially malignant. Here a case of gynandroblastoma occurring in a 30-year female is reported who gave history of irregular menstrual bleeding and pain abdomen, there were no signs of virilisation. Computed tomography scan showed a left adnexal mixed density pelvic mass suggesting malignant ovarian tumour. Histological study revealed, the tumour was composed of mixed sex cord elements with predominantly intermediate differentiated Sertoli-Leydig cell component and a second adult type granulosa cell component.
两性母细胞瘤是一种罕见的卵巢混合性性索间质肿瘤,文献报道的病例极少。这些肿瘤被认为具有潜在恶性。本文报告一例发生在30岁女性的两性母细胞瘤,患者有月经不规则出血和腹痛病史,无男性化体征。计算机断层扫描显示左附件区有一混合密度盆腔肿块,提示为恶性卵巢肿瘤。组织学研究显示,肿瘤由混合性性索成分组成,主要为中等分化的支持-莱迪希细胞成分和第二种成年型颗粒细胞成分。