Yang H, Wu J, Cheng J, Wang X, Wen L, Li K, Su H
Department of Epidemiology and Health Statistic, School of Public Health, Anhui Medical University, Hefei, China.
Hefei Center for Disease Control and Prevention, Hefei, China.
Public Health. 2017 Jan;142:201-207. doi: 10.1016/j.puhe.2015.03.018. Epub 2015 Apr 30.
To examine the relationship between relative humidity and childhood hand, foot and mouth disease (HFMD) in Hefei, China, and to explore whether the effect is different between urban and rural areas.
Retrospective ecological study.
A Poisson generalized linear model combined with a distributed lag non-linear model was used to examine the relationship between relative humidity and childhood HFMD in a temperate Chinese city during 2010-2012.
The effect of relative humidity on childhood HFMD increased above a humidity of 84%, with a 0.34% (95% CI: 0.23%-0.45%) increase of childhood HFMD per 1% increment of relative humidity. Notably, urban children, male children, and children aged 0-4 years appeared to be more vulnerable to the effect of relative humidity on HFMD.
This article study indicates that high relative humidity may trigger childhood HFMD in a temperate area, Hefei, particularly for those who are young and from urban areas.
探讨中国合肥地区相对湿度与儿童手足口病（HFMD）之间的关系，并探究城乡之间的影响是否存在差异。
回顾性生态学研究。
采用泊松广义线性模型结合分布滞后非线性模型，研究2010 - 2012年中国一个温带城市相对湿度与儿童手足口病之间的关系。
相对湿度超过84%时，其对儿童手足口病的影响增强，相对湿度每增加1%，儿童手足口病增加0.34%（95%CI：0.23% - 0.45%）。值得注意的是，城市儿童、男童以及0 - 4岁儿童似乎更容易受到相对湿度对手足口病影响的侵害。
本文研究表明，高相对湿度可能引发合肥这个温带地区的儿童手足口病，尤其是对那些年龄较小和来自城市地区的儿童。
