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择期和急性结直肠手术后老年患者术后谵妄:一项前瞻性队列研究。

Postoperative delirium in elderly after elective and acute colorectal surgery: A prospective cohort study.

机构信息

Department of Surgery, Amphia Hospital, Breda, The Netherlands.

Department of Surgery, Amphia Hospital, Breda, The Netherlands.

出版信息

Int J Surg. 2015 Jun;18:216-9. doi: 10.1016/j.ijsu.2015.04.080. Epub 2015 Apr 30.

Abstract

OBJECTIVE

To assess the frailty and the incidence of delirium in elderly patients undergoing elective and acute colorectal surgery in correlation with morbidity and mortality.

METHODS

Patients aged 65 years and older having elective and acute colorectal surgery, between April 2013 and December 2013 were included in a prospective database. Patients diagnosed with a colorectal carcinoma or diverticulitis who were operated on were included. Factors that characterize frailty of patients were noted. The incidence rates of delirium after elective and acute surgery were recorded. Delirium was diagnosed using the Delirium Observation Screening Scale (DOSS). Preoperative evaluation, surgical outcome including morbidity, hospital stay and mortality were analyzed.

RESULTS

Patients ≥ 65 years were included, 83 (75%) received elective and 28 (25%) acute surgery. The overall incidence of delirium was 21%, 18% for elective and 29% for patients having urgent surgery (p = 0.24). Patients with delirium were older than the non-delirious patients (median 82 years vs. 74 years; p < 0.001). Delirious patients showed higher incidence of adverse events. Hospital stay, mortality and discharge to a nursing home were significant higher in the delirious compared to the non-delirious group (p = 0.01; 0.01; 0.02 respectively).

CONCLUSION

High incidence of delirium was found in both acute and elective colorectal surgery. Delirium was associated with adverse outcomes.

摘要

目的

评估行择期和急性结直肠手术的老年患者的衰弱和谵妄发生率,并与发病率和死亡率相关。

方法

纳入 2013 年 4 月至 2013 年 12 月期间进行择期和急性结直肠手术的 65 岁及以上患者,并纳入接受结直肠癌或憩室炎手术的患者。记录患者衰弱的特征因素。记录择期和急性手术后谵妄的发生率。使用谵妄观察筛查量表(DOSS)诊断谵妄。分析术前评估、手术结果,包括发病率、住院时间和死亡率。

结果

纳入 65 岁及以上的患者,83 例(75%)接受择期手术,28 例(25%)接受急性手术。谵妄总发生率为 21%,择期手术为 18%,急诊手术为 29%(p=0.24)。谵妄患者比非谵妄患者年龄更大(中位数 82 岁比 74 岁;p<0.001)。谵妄患者发生不良事件的几率更高。谵妄组的住院时间、死亡率和出院到疗养院的比例均明显高于非谵妄组(p=0.01;0.01;0.02 分别)。

结论

在择期和急性结直肠手术中均发现谵妄发生率较高。谵妄与不良结局相关。

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