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对择期接受结直肠癌症手术的老年患者进行每日多学科评估与减少谵妄和老年综合征有关。

A daily multidisciplinary assessment of older adults undergoing elective colorectal cancer surgery is associated with reduced delirium and geriatric syndromes.

机构信息

Division of Geriatrics, Hospital Universitario de La Ribera (Alzira, Valencia, Spain), School of Nursing and Medicine, Universidad Católica de Valencia, San Vicente Martir, Spain.

Division of Geriatrics, Hospital Universitario de La Ribera (Alzira, Valencia, Spain), School of Nursing and Medicine, Universidad Católica de Valencia, San Vicente Martir, Spain.

出版信息

J Geriatr Oncol. 2019 Mar;10(2):298-303. doi: 10.1016/j.jgo.2018.08.013. Epub 2018 Sep 11.

Abstract

OBJECTIVES

Comprehensive geriatric assessment (CGA) has shown to benefit older patients undergoing urological and orthopedic surgery. However, this approach has been scarcely assessed in patients elected for colorectal surgery.

MATERIALS AND METHODS

Retrospective cohort of patients aged ≥70 years admitted for elective colorectal cancer surgery to a single hospital between 2008 and 2012. Upon admission, patients were assigned to a usual care (UC) plan or a CGA-based care (GS) plan conducted by a multidisciplinary team, according to standard clinical criteria.Analyzed outcomes included the incidence of delirium and other geriatric syndromes during hospital stay, mortality, readmissions, andnumber of perioperative complications.

RESULTS

The cohort included 310 patients, 203 assigned to the GS group and 107 to the UC group. Patients in the GS group had significantly lower Barthel and Lawton scores, higher prevalence of dementia and heart failure, and higher comorbidity burden. Fifty-four (17.5%) patientsexperienced delirium (23 [11.3%] and 31 [29.2%] in the GS and UC groups, respectively; p < .001), and 49 (15.8%) patient experienced other geriatric syndromes (21 [10.3%] and 28 [26.2%] in the GS and UC groups, respectively; p < .001). Serious complications were more frequent in the GS group: 154 (75.9%) vs 60 (56.1%) in the UC group; p < .001. No significant differences were observed between groups regarding readmissions, and in-hospital and post-discharge (1 year follow-up) mortality.

CONCLUSIONS

Despite the poorer clinical condition of patients in the GS group, the CGA-based intervention resulted in a lower incidence of delirium and other geriatric syndromes compared with the UC group.

摘要

目的

综合老年评估(CGA)已被证明有益于接受泌尿科和骨科手术的老年患者。然而,这种方法在接受结直肠手术的患者中几乎没有得到评估。

材料和方法

回顾性队列研究纳入 2008 年至 2012 年间在一家医院接受择期结直肠癌手术的年龄≥70 岁的患者。入院时,根据标准临床标准,患者被分配到常规护理(UC)计划或多学科团队进行的 CGA 护理(GS)计划。分析的结果包括住院期间谵妄和其他老年综合征的发生率、死亡率、再入院率和围手术期并发症的数量。

结果

该队列包括 310 名患者,203 名患者分配到 GS 组,107 名患者分配到 UC 组。GS 组患者的巴氏量表和洛文斯顿量表评分明显较低,痴呆和心力衰竭的患病率较高,合并症负担较重。54 名(17.5%)患者发生谵妄(GS 组 23 例[11.3%],UC 组 31 例[29.2%];p<0.001),49 名(15.8%)患者发生其他老年综合征(GS 组 21 例[10.3%],UC 组 28 例[26.2%];p<0.001)。GS 组严重并发症更常见:154 例(75.9%)比 UC 组 60 例(56.1%);p<0.001。两组间再入院率、住院和出院后(1 年随访)死亡率无显著差异。

结论

尽管 GS 组患者的临床状况较差,但与 UC 组相比,基于 CGA 的干预措施导致谵妄和其他老年综合征的发生率较低。

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