通过测量表观扩散系数的标准差提高扩散加权磁共振成像对肝血管瘤和转移瘤的鉴别能力。
Improved differentiation between hepatic hemangioma and metastases on diffusion-weighted MRI by measurement of standard deviation of apparent diffusion coefficient.
作者信息
Hardie Andrew D, Egbert Robert E, Rissing Michael S
机构信息
Medical University of South Carolina, Department of Radiology and Radiological Science, 169 Ashley Avenue, Charleston, SC, 29425.
Medical University of South Carolina, Department of Radiology and Radiological Science, 169 Ashley Avenue, Charleston, SC, 29425.
出版信息
Clin Imaging. 2015 Jul-Aug;39(4):654-8. doi: 10.1016/j.clinimag.2015.04.001. Epub 2015 Apr 22.
BACKGROUND
Diffusion-weighted magnetic resonance imaging (DW-MR) can be useful in the differentiation of hemangiomata from liver metastasis, but improved methods other than by mean apparent diffusion coefficient (mADC) are needed.
METHODS
A retrospective review identified 109 metastatic liver lesions and 86 hemangiomata in 128 patients who had undergone DW-MR. For each lesion, mADC and the standard deviation of the mean ADC (sdADC) were recorded and compared by receiver operating characteristic analysis.
RESULTS
Mean mADC was higher in benign hemangiomata (1.52±0.12 mm(2)/s) than in liver metastases (1.33±0.18 mm(2)/s), but there was significant overlap in values. The mean sdADC was lower in hemangiomata (101±17 mm(2)/s) than metastases (245±25 mm(2)/s) and demonstrated no overlap in values, which was significantly different (P<.0001).
CONCLUSIONS
Hemangiomata may be better able to be differentiated from liver metastases on the basis of sdADC than by mADC, although further studies are needed.
背景
磁共振扩散加权成像（DW-MR）有助于肝血管瘤与肝转移瘤的鉴别诊断，但除平均表观扩散系数（mADC）外，还需要改进其他方法。
方法
回顾性分析128例行DW-MR检查患者的资料，其中有109个肝转移瘤病灶和86个肝血管瘤病灶。记录每个病灶的mADC及平均ADC的标准差（sdADC），采用受试者工作特征分析进行比较。
结果
良性肝血管瘤的平均mADC（1.52±0.12mm²/s）高于肝转移瘤（1.33±0.18mm²/s），但两者数值有明显重叠。肝血管瘤的平均sdADC（101±17mm²/s）低于转移瘤（245±25mm²/s），且两者数值无重叠，差异有统计学意义（P<0.0001）。
结论
基于sdADC可能比mADC能更好地区分肝血管瘤与肝转移瘤，不过仍需进一步研究。
Zotero 插件