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散发性胰腺癌的早期检测:创新战略蓝图——白皮书

Early detection of sporadic pancreatic cancer: strategic map for innovation--a white paper.

作者信息

Kenner Barbara J, Chari Suresh T, Cleeter Deborah F, Go Vay Liang W

机构信息

From the *Kenner Family Research Fund, New York, NY; †Department of Medicine, Mayo Clinic, Rochester, MN; ‡Sawgrass Leadership Institute, Ponte Vedra Beach, FL; and §Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.

出版信息

Pancreas. 2015 Jul;44(5):686-92. doi: 10.1097/MPA.0000000000000369.

Abstract

Innovation leading to significant advances in research and subsequent translation to clinical practice is urgently necessary in early detection of sporadic pancreatic cancer. Addressing this need, the Early Detection of Sporadic Pancreatic Cancer Summit Conference was conducted by Kenner Family Research Fund in conjunction with the 2014 American Pancreatic Association and Japan Pancreas Society Meeting. International interdisciplinary scientific representatives engaged in strategic facilitated conversations based on distinct areas of inquiry: Case for Early Detection: Definitions, Detection, Survival, and Challenges; Biomarkers for Early Detection; Imaging; and Collaborative Studies. Ideas generated from the summit have led to the development of a Strategic Map for Innovation built upon 3 components: formation of an international collaborative effort, design of an actionable strategic plan, and implementation of operational standards, research priorities, and first-phase initiatives. Through invested and committed efforts of leading researchers and institutions, philanthropic partners, government agencies, and supportive business entities, this endeavor will change the future of the field and consequently the survival rate of those diagnosed with pancreatic cancer.

摘要

在散发性胰腺癌的早期检测方面,实现能推动研究取得重大进展并随后转化为临床实践的创新迫在眉睫。为满足这一需求,肯纳家族研究基金联合2014年美国胰腺协会和日本胰腺学会会议举办了散发性胰腺癌早期检测峰会。国际跨学科科学代表基于不同的研究领域进行了战略引导对话:早期检测的依据:定义、检测、生存率及挑战;早期检测的生物标志物;成像;以及合作研究。峰会上产生的想法促成了一个基于三个要素的创新战略地图的制定:形成国际合作努力、设计可操作的战略计划、以及实施操作标准、研究重点和第一阶段倡议。通过顶尖研究人员和机构、慈善合作伙伴、政府机构以及支持性商业实体的投入和坚定努力,这项工作将改变该领域的未来,从而提高胰腺癌患者的生存率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e88b/4467583/30f677431492/mpa-44-686-g001.jpg

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