• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

散发性胰腺癌的早期检测:创新战略蓝图——白皮书

Early detection of sporadic pancreatic cancer: strategic map for innovation--a white paper.

作者信息

Kenner Barbara J, Chari Suresh T, Cleeter Deborah F, Go Vay Liang W

机构信息

From the *Kenner Family Research Fund, New York, NY; †Department of Medicine, Mayo Clinic, Rochester, MN; ‡Sawgrass Leadership Institute, Ponte Vedra Beach, FL; and §Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.

出版信息

Pancreas. 2015 Jul;44(5):686-92. doi: 10.1097/MPA.0000000000000369.

DOI:10.1097/MPA.0000000000000369
PMID:25938853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4467583/
Abstract

Innovation leading to significant advances in research and subsequent translation to clinical practice is urgently necessary in early detection of sporadic pancreatic cancer. Addressing this need, the Early Detection of Sporadic Pancreatic Cancer Summit Conference was conducted by Kenner Family Research Fund in conjunction with the 2014 American Pancreatic Association and Japan Pancreas Society Meeting. International interdisciplinary scientific representatives engaged in strategic facilitated conversations based on distinct areas of inquiry: Case for Early Detection: Definitions, Detection, Survival, and Challenges; Biomarkers for Early Detection; Imaging; and Collaborative Studies. Ideas generated from the summit have led to the development of a Strategic Map for Innovation built upon 3 components: formation of an international collaborative effort, design of an actionable strategic plan, and implementation of operational standards, research priorities, and first-phase initiatives. Through invested and committed efforts of leading researchers and institutions, philanthropic partners, government agencies, and supportive business entities, this endeavor will change the future of the field and consequently the survival rate of those diagnosed with pancreatic cancer.

摘要

在散发性胰腺癌的早期检测方面,实现能推动研究取得重大进展并随后转化为临床实践的创新迫在眉睫。为满足这一需求,肯纳家族研究基金联合2014年美国胰腺协会和日本胰腺学会会议举办了散发性胰腺癌早期检测峰会。国际跨学科科学代表基于不同的研究领域进行了战略引导对话:早期检测的依据:定义、检测、生存率及挑战;早期检测的生物标志物;成像;以及合作研究。峰会上产生的想法促成了一个基于三个要素的创新战略地图的制定:形成国际合作努力、设计可操作的战略计划、以及实施操作标准、研究重点和第一阶段倡议。通过顶尖研究人员和机构、慈善合作伙伴、政府机构以及支持性商业实体的投入和坚定努力,这项工作将改变该领域的未来,从而提高胰腺癌患者的生存率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e88b/4467583/7d88c2752cdc/mpa-44-686-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e88b/4467583/30f677431492/mpa-44-686-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e88b/4467583/7d88c2752cdc/mpa-44-686-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e88b/4467583/30f677431492/mpa-44-686-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e88b/4467583/7d88c2752cdc/mpa-44-686-g002.jpg

相似文献

1
Early detection of sporadic pancreatic cancer: strategic map for innovation--a white paper.散发性胰腺癌的早期检测:创新战略蓝图——白皮书
Pancreas. 2015 Jul;44(5):686-92. doi: 10.1097/MPA.0000000000000369.
2
Early detection of sporadic pancreatic cancer: summative review.散发性胰腺癌的早期检测:综述
Pancreas. 2015 Jul;44(5):693-712. doi: 10.1097/MPA.0000000000000368.
3
Early Detection of Pancreatic Cancer: The Role of Industry in the Development of Biomarkers.胰腺癌的早期检测:行业在生物标志物开发中的作用
Pancreas. 2017 Nov/Dec;46(10):1238-1241. doi: 10.1097/MPA.0000000000000939.
4
Artificial Intelligence and Early Detection of Pancreatic Cancer: 2020 Summative Review.人工智能与胰腺癌早期检测:2020 年总结性回顾。
Pancreas. 2021 Mar 1;50(3):251-279. doi: 10.1097/MPA.0000000000001762.
5
Early Detection of Pancreatic Cancer-a Defined Future Using Lessons From Other Cancers: A White Paper.胰腺癌的早期检测——借鉴其他癌症的经验,明确未来方向:白皮书
Pancreas. 2016 Sep;45(8):1073-9. doi: 10.1097/MPA.0000000000000701.
6
Pancreatic cancer early detection: expanding higher-risk group with clinical and metabolomics parameters.胰腺癌早期检测:利用临床和代谢组学参数扩大高危人群范围。
World J Gastroenterol. 2015 Feb 14;21(6):1707-17. doi: 10.3748/wjg.v21.i6.1707.
7
Pancreatic cancer and cancer screening programs: from nihilism to hope.胰腺癌与癌症筛查项目:从虚无主义到希望
JOP. 2010 Nov 9;11(6):654-5.
8
Advances in pancreatic cancer research: moving towards early detection.胰腺癌研究进展:迈向早期检测
World J Gastroenterol. 2014 Aug 28;20(32):11241-8. doi: 10.3748/wjg.v20.i32.11241.
9
Early detection of sporadic pancreatic cancer: time for change.散发性胰腺癌的早期检测:变革之时。
Eur J Gastroenterol Hepatol. 2017 Aug;29(8):885-891. doi: 10.1097/MEG.0000000000000904.
10
Metastatic Pancreatic Cancer.转移性胰腺癌
J Invest Surg. 2018 Apr;31(2):151-152. doi: 10.1080/08941939.2017.1291774. Epub 2017 Mar 7.

引用本文的文献

1
B7 homolog 3 in pancreatic cancer.B7 同源物 3 在胰腺癌中的作用。
World J Gastroenterol. 2024 Aug 21;30(31):3654-3667. doi: 10.3748/wjg.v30.i31.3654.
2
A Quest for Survival: A Review of the Early Biomarkers of Pancreatic Cancer and the Most Effective Approaches at Present.求生之路:胰腺癌早期生物标志物综述及目前最有效的方法。
Biomolecules. 2024 Mar 19;14(3):364. doi: 10.3390/biom14030364.
3
A Simple Clinical Scoring System to Determine the Risk of Pancreatic Cancer in the General Population.一种用于确定普通人群胰腺癌风险的简易临床评分系统。

本文引用的文献

1
Early detection of sporadic pancreatic cancer: summative review.散发性胰腺癌的早期检测:综述
Pancreas. 2015 Jul;44(5):693-712. doi: 10.1097/MPA.0000000000000368.
2
KRAS and guanine nucleotide-binding protein mutations in pancreatic juice collected from the duodenum of patients at high risk for neoplasia undergoing endoscopic ultrasound.在内镜超声检查时,从患瘤风险高的患者十二指肠收集的胰液中的KRAS和鸟嘌呤核苷酸结合蛋白突变
Clin Gastroenterol Hepatol. 2015 May;13(5):963-9.e4. doi: 10.1016/j.cgh.2014.11.028. Epub 2014 Dec 4.
3
Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States.
Diagnostics (Basel). 2024 Mar 20;14(6):651. doi: 10.3390/diagnostics14060651.
4
Viscoelastic stiffening of gelatin hydrogels for dynamic culture of pancreatic cancer spheroids.明胶水凝胶的黏弹性增强用于胰腺癌球体的动态培养。
Acta Biomater. 2024 Mar 15;177:203-215. doi: 10.1016/j.actbio.2024.02.010. Epub 2024 Feb 12.
5
[Pancreatic cancer-screening or surveillance?].[胰腺癌筛查还是监测?]
Radiologie (Heidelb). 2023 Dec;63(12):908-915. doi: 10.1007/s00117-023-01227-3.
6
Artificial intelligence in pancreatic cancer: diagnosis, limitations, and the future prospects-a narrative review.人工智能在胰腺癌中的应用:诊断、局限性和未来前景——综述
J Cancer Res Clin Oncol. 2023 Aug;149(9):6743-6751. doi: 10.1007/s00432-023-04625-1. Epub 2023 Feb 4.
7
Epithelial to Mesenchymal Transition as Mechanism of Progression of Pancreatic Cancer: From Mice to Men.上皮-间质转化作为胰腺癌进展机制:从小鼠到人类
Cancers (Basel). 2022 Nov 24;14(23):5797. doi: 10.3390/cancers14235797.
8
Early Detection Initiative: A randomized controlled trial of algorithm-based screening in patients with new onset hyperglycemia and diabetes for early detection of pancreatic ductal adenocarcinoma.早期检测倡议:一项基于算法的筛查在新发高血糖和糖尿病患者中用于早期检测胰腺导管腺癌的随机对照试验。
Contemp Clin Trials. 2022 Feb;113:106659. doi: 10.1016/j.cct.2021.106659. Epub 2021 Dec 23.
9
Abnormal Findings on "T1WI or DWI or MRCP:" An Effective Boolean Interpretation Model in Discriminating Small Pancreatic Ductal Adenocarcinoma from Control Group.“T1WI或DWI或MRCP”上的异常表现:一种鉴别小胰管腺癌与对照组的有效布尔解释模型
J Clin Imaging Sci. 2021 Oct 12;11:54. doi: 10.25259/JCIS_158_2021. eCollection 2021.
10
Biomarkers in Pancreatic Cancer as Analytic Targets for Nanomediated Imaging and Therapy.胰腺癌中的生物标志物作为纳米介导成像和治疗的分析靶点
Materials (Basel). 2021 Jun 4;14(11):3083. doi: 10.3390/ma14113083.
预计 2030 年美国癌症发病与死亡人数:甲状腺癌、肝癌和胰腺癌带来的意外负担。
Cancer Res. 2014 Jun 1;74(11):2913-21. doi: 10.1158/0008-5472.CAN-14-0155.
4
Multitarget stool DNA testing for colorectal-cancer screening.多靶点粪便 DNA 检测用于结直肠癌筛查。
N Engl J Med. 2014 Apr 3;370(14):1287-97. doi: 10.1056/NEJMoa1311194. Epub 2014 Mar 19.
5
Detection of circulating pancreas epithelial cells in patients with pancreatic cystic lesions.检测胰腺囊性病变患者循环胰腺上皮细胞。
Gastroenterology. 2014 Mar;146(3):647-51. doi: 10.1053/j.gastro.2013.12.007. Epub 2013 Dec 13.
6
Clinical performance of an automated stool DNA assay for detection of colorectal neoplasia.用于检测结直肠肿瘤的自动化粪便 DNA 检测的临床性能。
Clin Gastroenterol Hepatol. 2013 Oct;11(10):1313-8. doi: 10.1016/j.cgh.2013.04.023. Epub 2013 Apr 29.
7
Pancreatic adenocarcinoma: ESMO-ESDO Clinical Practice Guidelines for diagnosis, treatment and follow-up.胰腺腺癌:ESMO-ESDO诊断、治疗及随访临床实践指南
Ann Oncol. 2012 Oct;23 Suppl 7:vii33-40. doi: 10.1093/annonc/mds224.
8
EMT and dissemination precede pancreatic tumor formation. EMT 和播散先于胰腺肿瘤形成。
Cell. 2012 Jan 20;148(1-2):349-61. doi: 10.1016/j.cell.2011.11.025.
9
Frequent detection of pancreatic lesions in asymptomatic high-risk individuals.频繁检测无症状高危人群的胰腺病变。
Gastroenterology. 2012 Apr;142(4):796-804; quiz e14-5. doi: 10.1053/j.gastro.2012.01.005. Epub 2012 Jan 12.
10
Next-generation stool DNA test accurately detects colorectal cancer and large adenomas.下一代粪便 DNA 检测能准确检测结直肠癌和大型腺瘤。
Gastroenterology. 2012 Feb;142(2):248-56; quiz e25-6. doi: 10.1053/j.gastro.2011.10.031. Epub 2011 Nov 4.