Xu Guang-Yue, Qiu Yong, Mao Hai-Jun
Department of Orthopaedics, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Am J Ther. 2016 Nov/Dec;23(6):e1320-e1328. doi: 10.1097/MJT.0000000000000228.
To determinate the optimal treatment for distal radius fractures (DRF) by comparing the pin-track infection (PTI) rates in patients treated with 7 surgical techniques [bridging external fixation (EF), nonbridging EF, K-wire fixation, plaster fixation, dorsal plating, dorsal and volar plating, and volar plating]. After an exhaustive search of electronic databases for relevant published studies, high-quality randomized controlled trails were selected for the present network meta-analysis based on predefined selection criteria. Statistical analyses of the extracted data were conducted using Stata 12.0 software. After careful selection, 19 randomized controlled trails were included in our network meta-analysis and contained a combined total of 1805 subjects who underwent various surgical procedures. The network meta-analysis results showed that compared with bridging EF for treating DRF, the nonbridging EF, plaster fixation, volar plating, and dorsal and volar plating showed statistically significant differences in PTI rates. Importantly, the surface under the cumulative ranking curve values of the surgical interventions revealed that the PTI rates of plaster fixation and of dorsal and volar plating were the lowest, suggesting that these 2 surgical techniques are optimal for DRFs treatment, compared with the other methods. Our results suggest that plaster fixation and dorsal and volar plating are the best surgical treatments for DRFs compared with 5 other most common techniques. Thus, plaster fixation and dorsal and volar plating emerge as the most effective and credible treatments in consideration of PTI rates.
通过比较采用7种手术技术[桥接外固定(EF)、非桥接EF、克氏针固定、石膏固定、背侧钢板固定、背侧和掌侧钢板固定以及掌侧钢板固定]治疗的患者的针道感染(PTI)率,来确定桡骨远端骨折(DRF)的最佳治疗方法。在对电子数据库进行全面搜索以查找相关已发表研究后,根据预先定义的选择标准,选择高质量的随机对照试验用于本网络荟萃分析。使用Stata 12.0软件对提取的数据进行统计分析。经过仔细筛选,19项随机对照试验被纳入我们的网络荟萃分析,总共包含1805名接受各种手术的受试者。网络荟萃分析结果表明,与采用桥接EF治疗DRF相比,非桥接EF、石膏固定、掌侧钢板固定以及背侧和掌侧钢板固定在PTI率方面显示出统计学上的显著差异。重要的是,手术干预的累积排名曲线下面积值表明,石膏固定以及背侧和掌侧钢板固定的PTI率最低,这表明与其他方法相比,这两种手术技术是DRF治疗的最佳选择。我们的结果表明,与其他5种最常用的技术相比,石膏固定以及背侧和掌侧钢板固定是DRF的最佳手术治疗方法。因此,考虑到PTI率,石膏固定以及背侧和掌侧钢板固定成为最有效且可靠的治疗方法。