使用高清微型摄像头对流出道移植物中的血栓及其与连续流全人工心脏的连接处进行植入后可视化观察。

Post-explant visualization of thrombi in outflow grafts and their junction to a continuous-flow total artificial heart using a high-definition miniaturized camera.

作者信息

Karimov Jamshid H, Horvath David, Sunagawa Gengo, Byram Nicole, Moazami Nader, Golding Leonard A R, Fukamachi Kiyotaka

机构信息

Department of Biomedical Engineering/ND20, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.

Department of Thoracic and Cardiovascular Surgery, Kaufman Center for Heart Failure, Miller Family Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA.

出版信息

J Artif Organs. 2015 Dec;18(4):354-7. doi: 10.1007/s10047-015-0839-8. Epub 2015 May 5.

DOI:10.1007/s10047-015-0839-8

PMID:25939428

Abstract

Post-explant evaluation of the continuous-flow total artificial heart in preclinical studies can be extremely challenging because of the device's unique architecture. Determining the exact location of tissue regeneration, neointima formation, and thrombus is particularly important. In this report, we describe our first successful experience with visualizing the Cleveland Clinic continuous-flow total artificial heart using a custom-made high-definition miniature camera.

摘要

由于连续流全人工心脏独特的结构，在临床前研究中对其进行植入后评估极具挑战性。确定组织再生、新生内膜形成和血栓的确切位置尤为重要。在本报告中，我们描述了使用定制的高清微型摄像头可视化克利夫兰诊所连续流全人工心脏的首次成功经验。