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[体外脂肪饱和的腹膜巨噬细胞的体内迁移]

[In vivo migration of peritoneal macrophages, saturated with fats in vitro].

作者信息

Pataki M, Lusztig G

出版信息

Morphol Igazsagugyi Orv Sz. 1989 Oct;29(4):243-8.

PMID:2594020
Abstract

Our experiments aimed at the in vitro development of cells similar to macrophage foam cells of vessel wall. Fatty macrophages were produced by Intralipid incubation of peritoneal macrophages and their motility was studied in vivo. Our results showed that fat-saturated, isotope and colloid-gold marked macrophages can get through the vessel wall, so they are able to in vivo migration.

摘要

我们的实验旨在体外培养与血管壁巨噬细胞泡沫细胞相似的细胞。通过用脂肪乳剂孵育腹膜巨噬细胞来制备富含脂肪的巨噬细胞,并在体内研究其运动性。我们的结果表明,脂肪饱和、同位素和胶体金标记的巨噬细胞能够穿透血管壁,因此它们能够在体内迁移。

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