Patil Jayaprakash, Ankireddy Hari, Wilkes Antony, Williams David, Lim Michael
Pinderfields Hospital, Mid-Yorkshire Hospitals NHS Trust, Wakefield, WF1 4DG, UK.
Department of Anesthetics, Intensive Care and Pain Medicine, University Hospital of Wales, Cardiff, CF14 4XN, Wales, UK.
J Clin Monit Comput. 2015 Dec;29(6):673-9. doi: 10.1007/s10877-015-9701-z. Epub 2015 May 5.
High injection pressure is one of the warning signs of intraneural injection, with animal models suggesting pressures higher than 69 or 176 kPa as high risk, and is normally detected subjectively and inaccurately. We describe a system improvised from common clinical components that uses Boyle's law to objectively measure injection pressure. The objectives of the study were to (1) Validate our improvised pressure gauge (IPG) by comparing the injection pressure as calculated by Boyle's law against the measured pressure and (2) Use the IPG to measure the range of injection pressures by two groups of anesthetic professionals using the "syringe feel" technique. Our IPG system consists of an extended 1 ml syringe attached to a 3-way stopcock, inserted between the syringe containing the local anesthetic injectate and the needle. The IPG was validated against a pressure calibration reference. 20 anesthesiologists and 20 anesthetic assistants were recruited to apply pressure to the 20 ml syringe in vitro while blinded to the attached IPG. The pressures were measured on three separate occasions for each participant. There was good agreement (<8 percent difference) between the measured and theoretical pressure values. Anesthesiologists exceeded the threshold of 69 kPa in 18 of a total of 60 attempts whereas anesthetic assistants exceeded the threshold in 30 attempts out of 60 attempts. Anesthetic assistants exerted a higher overall pressure of 80 kPa compared to 51 kPa for anesthesiologists-this was statistically significant (p = 0.027). Our improvised system is easily and rapidly assembled from common clinical equipment and shows promise as a monitor for inadvertent intraneural injection.
高注射压力是神经内注射的警示信号之一,动物模型表明压力高于69或176 kPa为高风险,且通常通过主观方式检测,结果不准确。我们描述了一种由常见临床组件临时拼凑而成的系统,该系统利用波义耳定律客观测量注射压力。本研究的目的是:(1)通过比较根据波义耳定律计算的注射压力与测量压力来验证我们的简易压力计(IPG);(2)使用IPG测量两组麻醉专业人员采用“注射器手感”技术时的注射压力范围。我们的IPG系统由一个延长的1 ml注射器连接一个三通旋塞组成,插入装有局部麻醉注射液的注射器和针头之间。IPG对照压力校准参考进行了验证。招募了20名麻醉医生和20名麻醉助手,在对所连接的IPG不知情的情况下,在体外对20 ml注射器施加压力。对每位参与者在三个不同场合测量压力。测量压力值与理论压力值之间具有良好的一致性(差异<8%)。在总共60次尝试中,麻醉医生有18次超过了69 kPa的阈值,而麻醉助手在60次尝试中有30次超过该阈值。麻醉助手施加的总体压力更高,为80 kPa,而麻醉医生为51 kPa,这具有统计学意义(p = 0.027)。我们的简易系统可轻松快速地由常见临床设备组装而成,有望作为意外神经内注射的监测工具。