Chang Chih-Chen, Lee Chia-Jie, Ou Liang-Shiou, Wang Chao-Jan, Huang Yhu-Chering
a Department of Medical Imaging and Intervention , Chang Gung Memorial Hospital , Linkou , Taiwan.
b Department of Pediatrics , Chang Gung Memorial Hospital , Linkou , Taiwan.
Paediatr Int Child Health. 2016 Aug;36(3):232-4. doi: 10.1179/2046905515Y.0000000005.
Cat scratch disease (CSD) can present as a systemic disease in 5-10% of cases and lead to various disease entities. A previously healthy 16-month-old boy presented with fever for 7 days without other obvious symptoms. Abdominal computed tomography scan demonstrated enlarged right inguinal lymph nodes and multiple small round hypodensities in the spleen. Despite antibiotic treatment for 1 week, the fever persisted and the intrasplenic lesions progressed. Inguinal lymph node biopsy confirmed CSD by immunohistochemistry staining. The diagnosis of CSD was also supported by a history of contact, imaging and serological findings. The patient recovered after treatment with azithromycin for a total of 5 weeks and, in serial follow-up, the hepatosplenic micro-abscesses resolved after 4th months.
猫抓病(CSD)在5%至10%的病例中可表现为全身性疾病,并导致各种疾病实体。一名此前健康的16个月大男孩出现发热7天,无其他明显症状。腹部计算机断层扫描显示右侧腹股沟淋巴结肿大,脾脏内有多个小圆形低密度影。尽管使用抗生素治疗1周,发热仍持续,脾脏内病变进展。腹股沟淋巴结活检通过免疫组织化学染色确诊为CSD。接触史、影像学和血清学检查结果也支持CSD的诊断。患者接受阿奇霉素治疗共5周后康复,在连续随访中,肝脾微脓肿在4个月后消退。