Nguyen Martin, Singh Sheraj, Sam Bevan, Llerena Richard, Frank Abigail, Mabalot Marinella
Radiology, West Virginia School of Osteopathic Medicine, Lewisburg, USA.
Medicine, West Virginia School of Osteopathic Medicine, Lewisburg, USA.
Cureus. 2024 Aug 4;16(8):e66134. doi: 10.7759/cureus.66134. eCollection 2024 Aug.
We reported the case of a 13-year-old immunocompetent boy presenting with a right cervical neck mass. He complained of fatigue, back pain, coughing, and a right neck mass persisting for three months. He did not have a fever, but his parents reported he had lost 20 lbs. in the past six months without any change in diet or appetite. They are also very concerned about the risk of malignancy. During the initial work-up, there was no abnormality in the complete blood count. During the follow-up visit 10 days later, he complained of new-onset dysphagia and throat pain. The mass was about 5 cm on the right neck, poorly mobile, and mildly tender to palpation. It looks significantly different compared to the first visit. Blood serology tests were indicated, and titers of cytomegalovirus (CMV), Epstein-Barr virus (EBV), and toxoplasma were not reactive. However, serology detected that IgM and IgG titers to were ≥1:20 and ≥1:1024, respectively. A fine needle aspiration (FNA) of the mass on the same day revealed lymphoid proliferation. Afterward, the patient was treated with amoxicillin-clavulanic acid for two weeks. After three weeks, the mass almost disappeared, and the patient reported a remarkable improvement in symptoms. This case report is a helpful reminder that should be suspected on the differential diagnoses in a case of lymphadenopathy associated with non-specific symptoms such as fatigue, back pain, and weight loss.
我们报告了一例13岁免疫功能正常男孩,其表现为右侧颈部肿块。他主诉疲劳、背痛、咳嗽,右侧颈部肿块持续三个月。他没有发热,但他的父母报告他在过去六个月体重减轻了20磅,饮食和食欲没有任何变化。他们也非常担心恶性肿瘤的风险。在初始检查期间,全血细胞计数没有异常。在10天后的随访中,他主诉出现新发吞咽困难和咽痛。右侧颈部肿块约5厘米,活动度差,触诊时有轻度压痛。与首次就诊相比,外观有明显不同。进行了血液血清学检查,巨细胞病毒(CMV)、EB病毒(EBV)和弓形虫的滴度均无反应。然而,血清学检测发现针对 的IgM和IgG滴度分别≥1:20和≥1:1024。同一天对肿块进行细针穿刺抽吸(FNA)显示为淋巴细胞增殖。此后,患者接受阿莫西林 - 克拉维酸治疗两周。三周后,肿块几乎消失,患者报告症状有显著改善。本病例报告有助于提醒,在伴有疲劳、背痛和体重减轻等非特异性症状的淋巴结病病例的鉴别诊断中应怀疑 。 (注:原文中“针对 的IgM和IgG滴度”这里“针对的”后面内容缺失)