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Hemagglutinin stem reactive antibody response in individuals immunized with a seasonal influenza trivalent vaccine.

作者信息

Zhao Xiaopeng, Qin Kun, Guo Jinlei, Wang Donghong, Li Zi, Zhu Wenfei, Liu Liqi, Wang Dayan, Shu Yuelong, Zhou Jianfang

机构信息

National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, 102206 China.

出版信息

Protein Cell. 2015 Jun;6(6):453-457. doi: 10.1007/s13238-015-0160-6.

DOI:10.1007/s13238-015-0160-6
PMID:25940943
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4444808/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ae1/4444808/d1593e7b784e/13238_2015_160_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ae1/4444808/309b269acb3b/13238_2015_160_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ae1/4444808/d1593e7b784e/13238_2015_160_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ae1/4444808/309b269acb3b/13238_2015_160_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ae1/4444808/d1593e7b784e/13238_2015_160_Fig2_HTML.jpg

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引用本文的文献

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Sci Rep. 2018 Jun 5;8(1):8628. doi: 10.1038/s41598-018-26538-7.

本文引用的文献

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Rapid development of broadly influenza neutralizing antibodies through redundant mutations.通过冗余突变快速产生广谱流感中和抗体。
Nature. 2014 Dec 18;516(7531):418-22. doi: 10.1038/nature13764. Epub 2014 Oct 5.
2
Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans.人类接种H5N1疫苗后对流感血凝素茎区产生广泛交叉反应性抗体应答
Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13133-8. doi: 10.1073/pnas.1414070111. Epub 2014 Aug 25.
3
World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects.
《世界医学协会赫尔辛基宣言:涉及人类受试者的医学研究伦理原则》
JAMA. 2013 Nov 27;310(20):2191-4. doi: 10.1001/jama.2013.281053.
4
Universal anti-neuraminidase antibody inhibiting all influenza A subtypes.通用抗神经氨酸酶抗体抑制所有甲型流感亚型。
Antiviral Res. 2013 Nov;100(2):567-74. doi: 10.1016/j.antiviral.2013.09.018. Epub 2013 Sep 30.
5
Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells.大流行性 H1N1 流感疫苗在人体内诱导出一种有利于广泛交叉反应性记忆 B 细胞的回忆反应。
Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9047-52. doi: 10.1073/pnas.1118979109. Epub 2012 May 21.
6
Potent neutralization of influenza A virus by a single-domain antibody blocking M2 ion channel protein.单域抗体通过阻断 M2 离子通道蛋白有效中和流感 A 病毒。
PLoS One. 2011;6(12):e28309. doi: 10.1371/journal.pone.0028309. Epub 2011 Dec 2.
7
Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin.广谱中和人抗体,识别流感病毒血凝素的受体结合口袋。
Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14216-21. doi: 10.1073/pnas.1111497108. Epub 2011 Aug 8.
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A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins.一种从浆细胞中筛选出的能够与甲型流感血凝素 1 型和 2 型结合的中和抗体。
Science. 2011 Aug 12;333(6044):850-6. doi: 10.1126/science.1205669. Epub 2011 Jul 28.
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Wide prevalence of heterosubtypic broadly neutralizing human anti-influenza A antibodies.广泛存在异源广谱中和性抗甲型流感人抗体。
Clin Infect Dis. 2011 Apr 15;52(8):1003-9. doi: 10.1093/cid/cir121.
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Optimal vaccination strategies for 2009 pandemic H1N1 and seasonal influenza vaccines in humans.人类 2009 年大流行 H1N1 和季节性流感疫苗的最佳接种策略。
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