PG and Research Department of Chemistry, Muthurangam Government Arts College, Vellore 632002, Tamilnadu, India.
Department of Chemistry, Voorhees College, Vellore 632001, Tamilnadu, India.
Ecotoxicol Environ Saf. 2015 Nov;121:116-20. doi: 10.1016/j.ecoenv.2015.04.044. Epub 2015 May 2.
In the present investigation, an efficient and environmentally adopted synthesis of triaryl substituted imidazole in one-pot was reported. The multicomponent reaction between various aldehydes, benzil, benzoin, ammonium acetate and glycine under solvent free condition has been explained. Instead of using toxic reagents for the synthesis of heterocyclic compounds, Glycine has been selected as a green catalyst due to simple work-up procedure, shorter reaction time and high yield. The synthesized imidazole derivatives on further treatment with phosphorous oxychloride resulted in an organophosphorous containing N-heterocyclic compound (N-P) thus by altering acidic hydrogen of imidazole. Further, N-P was reacted with polyvinyl alcohol resulted into organophosphorous N-heterocyclic vinyl polymers. The synthesized vinyl polymers were characterized using, FTIR, NMR and Mass spectral studies. Results of the spectral studies were well supported the formation of the compounds. Thermal stability have also been studied using TGA.
在本研究中，报告了一种在一锅法中高效且环保地合成三芳基取代咪唑的方法。该多组分反应是在无溶剂条件下，通过各种醛、二苯甲酮、安息香、醋酸铵和甘氨酸之间进行的。为了避免使用有毒试剂合成杂环化合物，甘氨酸被选为绿色催化剂，因为它具有简单的后处理步骤、较短的反应时间和较高的产率。合成的咪唑衍生物进一步与氧氯化磷反应，生成含有有机磷的 N-杂环化合物（N-P），从而改变了咪唑的酸性氢。进一步，N-P 与聚乙烯醇反应生成有机磷 N-杂环乙烯基聚合物。通过傅里叶变换红外光谱、核磁共振谱和质谱研究对合成的乙烯基聚合物进行了表征。光谱研究结果很好地支持了化合物的形成。还使用 TGA 研究了热稳定性。
