Shinkarenko V S, Kol'iantes Khara Kh, Kulikova O S
Biull Eksp Biol Med. 1990 Aug;110(8):145-8.
The influence of normo- (38 degrees C), hyper- (42 degrees C) and hypothermia (20 degrees C) on microcirculatory disturbances caused by acute local ischemia of the small intestine was investigated with the help of biomicroscopy as well as morphological methods. Ischemia was modeled by ligation of the intestine look eventrated through the abdominal wall incision of a rat onto the microscope stage for 1 h. It was shown that hyperthermia intensified microcirculatory disorders and stimulated destructive processes in tissues and hypothermia promoting microcirculation and decreasing metabolism and restrained the development of these processes. Important peculiarity of the microvascular response to ischemia, hyper- and hypothermia was revealed: heterogeneity of the reaction of different parts of microvascular bed. Appropriate evaluation of the microcirculation state in such conditions can be obtained taking into account not only the qualitative character of microvascular reaction but also an extent of this reaction manifestation in different parts of microvascular bed.
借助生物显微镜以及形态学方法，研究了正常体温（38摄氏度）、高热（42摄氏度）和低温（20摄氏度）对小肠急性局部缺血所致微循环障碍的影响。通过将经大鼠腹壁切口引出并置于显微镜载物台上的肠袢结扎1小时来模拟缺血。结果表明，高热加剧了微循环障碍并刺激了组织中的破坏过程，而低温促进了微循环、降低了代谢并抑制了这些过程的发展。揭示了微血管对缺血、高热和低温反应的一个重要特点：微血管床不同部位反应的异质性。在这种情况下，不仅要考虑微血管反应的定性特征，还要考虑这种反应在微血管床不同部位的表现程度，才能对微循环状态进行恰当评估。
