Lee Chang-Ro, Lee Jung Hun, Kang Lin-Woo, Jeong Byeong Chul, Lee Sang Hee
National Leading Research Laboratory of Drug Resistance Proteomics, Department of Biological Sciences, Myongji University, 116 Myongjiro, Yongin, Gyeonggido 449-728, Republic of Korea.
Department of Biological Sciences, Konkuk University, 1 Hwayangdong, Gwangjingu, Seoul 143-701, Republic of Korea.
Biomed Res Int. 2015;2015:214021. doi: 10.1155/2015/214021. Epub 2015 Apr 5.
Widespread antimicrobial use and concomitant resistance have led to a significant threat to public health. Because inappropriate use and overuse of antibiotics based on insufficient knowledge are one of the major drivers of antibiotic resistance, education about prudent antibiotic use aimed at both the prescribers and the public is important. This review investigates recent studies on the effect of interventions for promoting prudent antibiotics prescribing. Up to now, most educational efforts have been targeted to medical professionals, and many studies showed that these educational efforts are significantly effective in reducing antibiotic prescribing. Recently, the development of educational programs to reduce antibiotic use is expanding into other groups, such as the adult public and children. The investigation of the contents of educational programs for prescribers and the public demonstrates that it is important to develop effective educational programs suitable for each group. In particular, it seems now to be crucial to develop appropriate curricula for teaching medical and nonmedical (pharmacy, dentistry, nursing, veterinary medicine, and midwifery) undergraduate students about general medicine, microbial virulence, mechanism of antibiotic resistance, and judicious antibiotic prescribing.
广泛使用抗菌药物以及随之产生的耐药性已对公众健康构成重大威胁。由于基于知识不足而不恰当使用和过度使用抗生素是抗生素耐药性的主要驱动因素之一，因此针对开处方者和公众开展合理使用抗生素的教育很重要。本综述调查了近期关于促进合理开具抗生素处方干预措施效果的研究。到目前为止，大多数教育工作都针对医学专业人员，许多研究表明，这些教育工作在减少抗生素处方方面具有显著效果。最近，减少抗生素使用的教育项目发展到了其他群体，如成年公众和儿童。对开处方者和公众教育项目内容的调查表明，制定适合每个群体的有效教育项目很重要。特别是，为医学和非医学（药学、牙科、护理、兽医学和助产学）本科学生开设关于普通医学、微生物毒力、抗生素耐药机制和合理开具抗生素处方的适当课程，现在看来至关重要。
