Ferenczy Peter Alexander von Harbach, Dalcegio Maiara, Koehler Marcela, Pereira Thiago Silveira, Moreira Hamilton, Luciane Bugmann Moreira
Anterior Segment Sector, Hospital de Olhos do Paraná, Curitiba, PR, Brazil.
Refractive Surgery Sector, Hospital de Olhos do Paraná, Curitiba, PR, Brazil.
Arq Bras Oftalmol. 2015 Mar-Apr;78(2):76-81. doi: 10.5935/0004-2749.20150021.
To compare visual outcomes, corneal astigmatism, and keratometric readings in patients with keratoconus who underwent intrastromal corneal ring implantation (ICRSI) alone with those who underwent ICRSI combined with ultraviolet A riboflavin-mediated corneal collagen crosslinking (CXL).
Pre- and post-operative best-corrected distance visual acuity (BCDVA), spherical error, cylindrical error, and mean keratometry were retrospectively compared over a period of 2 years in patients with keratoconus who underwent only ICRSI (group 1) versus those in patients who underwent combined ICRSI-CXL (group 2).
Thirty-two eyes of 31 patients were evaluated. CXL was performed in 10 cases (31%), and there were no complications or need for ring repositioning. BCDVA improved from 0.54 to 0.18 in the group 1 and from 0.56 to 0.17 in the group 2. Spherical and cylindrical errors and mean keratometry values significantly decreased in both groups. No patient postoperatively had visual acuity (VA) of less than 20/60 on refraction, and 78% exhibited VA better than or equal to 20/40 with spectacles (72% of group 1 and 90% of group 2). Improvement in the spherical equivalent (SE) value was observed in the group 1 (from -5.89 ± 3.37 preoperatively to -2.65 ± 2.65 postoperatively; p<0.05) and group 2 (from -6.91 ± 1.93 preoperatively to -2.11 ± 3.01 postoperatively; p<0.05).
Both techniques can be considered safe and effective in improving VA and refractive SE values, in decreasing the curvature of the cone apex in the topographical analysis, and in decreasing corrected diopters postoperatively in patients with keratoconus.
比较单纯接受基质内角膜环植入术(ICRSI)的圆锥角膜患者与接受ICRSI联合紫外线A核黄素介导的角膜胶原交联术(CXL)的圆锥角膜患者的视力结果、角膜散光和角膜曲率读数。
回顾性比较圆锥角膜患者在2年时间内仅接受ICRSI(第1组)与接受ICRSI-CXL联合手术(第2组)的术前和术后最佳矫正远视力(BCDVA)、球镜度数、柱镜度数和平均角膜曲率。
对31例患者的32只眼进行了评估。10例(31%)进行了CXL,未出现并发症或需要重新定位角膜环的情况。第1组的BCDVA从0.54提高到0.18,第2组从0.56提高到0.17。两组的球镜和柱镜度数以及平均角膜曲率值均显著降低。术后没有患者验光视力(VA)低于20/60,78%的患者戴眼镜时视力优于或等于20/40(第1组为72%,第2组为90%)。第1组(术前为-5.89±3.37,术后为-2.65±2.65;p<0.05)和第2组(术前为-6.91±1.93,术后为-2.11±3.01;p<0.05)的等效球镜(SE)值均有改善。
两种技术在改善圆锥角膜患者的视力和屈光SE值、降低地形分析中圆锥顶点的曲率以及降低术后矫正屈光度方面均可认为是安全有效的。