Lara Humberto Herman, Alanís-Garza Eduardo Javier, Estrada Puente María Fernanda, Mureyko Lucía Liliana, Alarcón Torres David Alejandro, Ixtepan Turrent Liliana
Departamento de Ciencias Básicas, División de Ciencia de la Salud, Universidad de Monterrey, Monterrey, N.L., Mexico.
Gac Med Mex. 2015 Mar-Apr;151(2):245-51.
Alzheimer's disease is the most common cause of dementia in the world; symptoms first appear after age 65 and have a progressive evolution. Expecting an increase on its incidence and knowing there is currently no cure for Alzheimer's disease, it is a necessity to prevent progression. The change in diet due to globalization may explain the growth of the incidence in places such as Japan and Mediterranean countries, which used to have fewer incidences. There is a direct correlation between disease progression and the increased intake of alcohol, saturated fats, and red meat. Therefore, we find obesity and higher serum levels in cholesterol due to saturated fat as a result. A way to decrease the progression of Alzheimer's is through a diet rich in polipheno/es (potent antioxidants), unsaturated fats (monounsaturated and polyunsaturated), fish, vegetable fa t, fruits with low glycemic index, and a moderate consumption of red wine. Through this potent antioxidant diet we accomplish the prevention of dementia and the progression of Alzheimer's disease. This article emphasizes the food and other components that have been demonstrated to decrease the oxidative stress related to these progressive diseases.
阿尔茨海默病是全球痴呆最常见的病因;症状首次出现在65岁之后,并呈进行性发展。鉴于其发病率预计会上升,且目前尚无治愈阿尔茨海默病的方法,预防病情进展很有必要。全球化导致的饮食变化或许可以解释日本和地中海国家等地发病率的增长,这些地区过去发病率较低。疾病进展与酒精、饱和脂肪和红肉摄入量增加直接相关。因此,我们发现由于饱和脂肪导致肥胖以及血清胆固醇水平升高。减少阿尔茨海默病进展的一种方法是通过富含多酚(强效抗氧化剂)、不饱和脂肪(单不饱和和多不饱和脂肪)、鱼类、植物油、低血糖指数水果以及适量饮用红酒的饮食。通过这种富含强效抗氧化剂的饮食,我们可以预防痴呆以及阿尔茨海默病的进展。本文强调了已被证明可降低与这些进展性疾病相关的氧化应激的食物及其他成分。