Salehi Mohammadgharib, Nalaini Farhad, Izadi Babak, Setayeshi Khosro, Rezaei Mansour, Naseri Seyyed Nooredin
Radiology Department, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Glob J Health Sci. 2014 Nov 26;7(3):147-52. doi: 10.5539/gjhs.v7n3p147.
We intended to compare gray-scale vs. color Doppler ultrasound findings in cold thyroid nodules. Sixty-four patients with cold thyroid nodules for whom the presumptive diagnosis of malignancy (based on isotope scan study) had been made were consecutively included. They underwent gray-scale and color Doppler sonography studies. Based on histopathologic examination of surgically removed nodules, there were respectively 25 (39%) and 39 (61%) malignant and benign nodules. On color Doppler sonography, preference central hypervascularity was the most common finding in malignant nodules (17 nodules, 68%). Among benign nodules, preference perinodular hypervascularity was the most common finding (26 nodules, 66.7%). The most sensitive and specific Doppler sonography findings for malignant nodules were preference central hypervascularity (68%) and only central vascularity (97%), respectively. On gray-scale sonography, absent halo sign was the most common finding in malignant nodules (20 nodules, 80%). Among benign nodules, microcalcification was the most common finding which was reported in 12 nodules (30.7%). Hypoechogenicity was the most specific finding (76.9%) for malignant nodules. Since both gray-scale and color Doppler ultrasonography are inexpensive, non-invasive, and accessible methods to diagnose thyroid malignant cold nodules, it is recommended that these methods be applied by clinicians to assist or even substitute other invasive methods.
我们旨在比较冷性甲状腺结节的灰阶超声与彩色多普勒超声检查结果。连续纳入64例经同位素扫描研究初步诊断为恶性（基于此）的冷性甲状腺结节患者。他们接受了灰阶和彩色多普勒超声检查。根据手术切除结节的组织病理学检查，分别有25个（39%）恶性结节和39个（61%）良性结节。在彩色多普勒超声检查中，恶性结节最常见的表现是偏向中央血管增多（17个结节，68%）。在良性结节中，最常见的表现是偏向结节周围血管增多（26个结节，66.7%）。恶性结节最敏感和特异的多普勒超声表现分别是偏向中央血管增多（68%）和仅中央血管存在（97%）。在灰阶超声检查中，恶性结节最常见的表现是无晕征（20个结节，80%）。在良性结节中，最常见的表现是微钙化，12个结节（30.7%）有此表现。低回声是恶性结节最具特异性的表现（76.9%）。由于灰阶和彩色多普勒超声检查都是诊断甲状腺恶性冷结节的廉价、非侵入性且可及的方法，建议临床医生应用这些方法来辅助甚至替代其他侵入性方法。
