• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

化疗后腹水样本中促结缔组织增生性小圆细胞肿瘤的异常形态。

Unusual morphology of desmoplastic small round cell tumor from an ascitic fluid in the postchemotherapy setting.

作者信息

González-Arango Ricardo, Castro-Villabón Diana, Barrera-Herrera Luis E, Palau Mauricio, Rodríguez-Urrego Paula A

机构信息

School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia.

Department of Pathology, Hospital Universitario Fundación Santa Fe de Bogotá, Universidad de Los Andes, Bogotá, Colombia.

出版信息

J Cytol. 2015 Jan-Mar;32(1):46-9. doi: 10.4103/0970-9371.155237.

DOI:10.4103/0970-9371.155237
PMID:25948947
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4408680/
Abstract

Desmoplastic small round cell tumor (DSRCT) is a malignant neoplasm that most often presents in male adolescents as an abdominal mass. Cytological features have been previously described, but only two reports noted post chemotherapy changes on effusions. We report a case of a 15-year-old male with DSRCT status postchemotherapy that presented with ascitis. Unusual morphology was seen: Numerous malignant large and single cells with prominent nucleoli and abundant cytoplasm in a background without the stroma, occasional mitosis, and the abundant apoptosis. Cell block immunocytochemistry was confirmatory. Awareness of the postchemotherapy changes in this tumor will allow us to diagnose recurrence.

摘要

促结缔组织增生性小圆细胞肿瘤（DSRCT）是一种恶性肿瘤，最常发生于男性青少年，表现为腹部肿块。其细胞学特征此前已有描述，但仅有两篇报道提及化疗后积液的变化。我们报告一例15岁男性DSRCT患者，化疗后出现腹水。观察到不寻常的形态：在无基质的背景中有大量具有明显核仁及丰富细胞质的恶性大细胞和单个细胞，偶见有丝分裂及大量凋亡。细胞块免疫细胞化学检查得以确诊。了解该肿瘤化疗后的变化将有助于我们诊断复发情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b27/4408680/c9273583fc67/JCytol-32-46-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b27/4408680/c9273583fc67/JCytol-32-46-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b27/4408680/c9273583fc67/JCytol-32-46-g001.jpg

相似文献

1
Unusual morphology of desmoplastic small round cell tumor from an ascitic fluid in the postchemotherapy setting.化疗后腹水样本中促结缔组织增生性小圆细胞肿瘤的异常形态。
J Cytol. 2015 Jan-Mar;32(1):46-9. doi: 10.4103/0970-9371.155237.
2
Cytology of desmoplastic small round-cell tumor: comparison of pre- and post-chemotherapy fine-needle aspiration biopsies.促纤维组织增生性小圆细胞瘤的细胞学：化疗前后细针穿刺活检的比较
Cancer. 2007 Feb 25;111(1):41-6. doi: 10.1002/cncr.22421.
3
Desmoplastic small round cell tumor with sphere-like clusters mimicking adenocarcinoma.具有类似腺癌的球形簇的促纤维组织增生性小圆细胞肿瘤。
Diagn Cytopathol. 2015 Mar;43(3):214-7. doi: 10.1002/dc.23174. Epub 2014 May 13.
4
A 23-Year-Old Joradanian Woman with a Desmoplastic Small Round Cell Tumor Involving the Ovary.一名患有促纤维增生性小圆细胞肿瘤累及卵巢的23岁约旦女性。
Am J Case Rep. 2019 Nov 14;20:1675-1678. doi: 10.12659/AJCR.919488.
5
Fine-needle aspiration in desmoplastic small round cell tumor: a report of 10 new tumors in 8 patients with clinicopathological and molecular correlations with review of the literature.促纤维增生性小圆细胞肿瘤的细针穿刺抽吸：8 例患者的 10 例新肿瘤的临床病理和分子学相关性报告，并进行文献复习。
Cancer Cytopathol. 2014 May;122(5):386-93. doi: 10.1002/cncy.21415. Epub 2014 Mar 17.
6
Desmoplastic round cell tumor of childhood: can cytology with immunocytochemistry serve as an alternative for tissue diagnosis?儿童促纤维增生性圆细胞肿瘤：细胞病理学联合免疫细胞化学能否作为组织学诊断的替代方法？
Diagn Cytopathol. 2005 Jun;32(6):330-5. doi: 10.1002/dc.20244.
7
Cytology of desmoplastic small round cell tumor.促纤维增生性小圆细胞肿瘤的细胞学
Cancer. 2002 Feb 25;96(1):21-31. doi: 10.1002/cncr.10316.
8
Sister Mary Joseph nodule caused by metastatic desmoplastic small round cell tumor: A clinicopathological report.转移性促纤维组织增生性小圆细胞肿瘤所致玛丽·约瑟夫修女结节：一份临床病理报告
Mol Clin Oncol. 2016 Nov;5(5):557-561. doi: 10.3892/mco.2016.1002. Epub 2016 Aug 24.
9
[Desmoplastic small round cell tumor: a clinicopathologic study of 15 cases].促纤维增生性小圆细胞肿瘤：15例临床病理研究
Zhonghua Bing Li Xue Za Zhi. 2005 Oct;34(10):650-5.
10
Sequence confirmation of the EWS-WT1 fusion gene transcript in the peritoneal effusion of a patient with desmoplastic small round cell tumor.促纤维增生性小圆细胞肿瘤患者腹腔积液中EWS-WT1融合基因转录本的序列确认
Diagn Cytopathol. 2003 Dec;29(6):341-3. doi: 10.1002/dc.10397.

本文引用的文献

1
Cytology of desmoplastic small round-cell tumor: comparison of pre- and post-chemotherapy fine-needle aspiration biopsies.促纤维组织增生性小圆细胞瘤的细胞学：化疗前后细针穿刺活检的比较
Cancer. 2007 Feb 25;111(1):41-6. doi: 10.1002/cncr.22421.
2
Desmoplastic small round cell tumors: cytologic, histologic, and immunohistochemical features.促纤维增生性小圆细胞瘤：细胞学、组织学及免疫组化特征
Arch Pathol Lab Med. 2006 May;130(5):728-32. doi: 10.5858/2006-130-728-DSRCTC.
3
Desmoplastic small round cell tumour: Cytological and immunocytochemical features.
促纤维组织增生性小圆细胞瘤：细胞学及免疫细胞化学特征
Cytojournal. 2005 Mar 18;2(1):6. doi: 10.1186/1742-6413-2-6.
4
Cytology of desmoplastic small round cell tumor.促纤维增生性小圆细胞肿瘤的细胞学
Cancer. 2002 Feb 25;96(1):21-31. doi: 10.1002/cncr.10316.
5
Intraabdominal desmoplastic small round cell tumor: report of a case with fine needle aspiration, cytologic diagnosis and molecular confirmation.腹腔促结缔组织增生性小圆细胞肿瘤：1例经细针穿刺抽吸、细胞学诊断及分子学确诊的病例报告
Acta Cytol. 2001 Jul-Aug;45(4):617-21. doi: 10.1159/000327875.
6
Intraabdominal desmoplastic small round cell tumor: cytopathologic findings in two cases.腹腔促结缔组织增生性小圆细胞肿瘤：2例细胞病理学表现
Diagn Cytopathol. 1998 Jun;18(6):449-52. doi: 10.1002/(sici)1097-0339(199806)18:6<449::aid-dc13>3.0.co;2-h.
7
Cytology of fluids from pleural, peritoneal and pericardial cavities in children. A comprehensive survey.儿童胸腔、腹腔和心包腔积液的细胞学检查。一项综合调查。
Acta Cytol. 1994 Mar-Apr;38(2):209-17.
8
Desmoplastic small round cell tumor presenting in pleural fluid and accompanied by desmin-positive mesothelial cells.发生于胸腔积液并伴有结蛋白阳性间皮细胞的促纤维增生性小圆细胞肿瘤。
Acta Cytol. 1995 Mar-Apr;39(2):377-8.
9
Small round cell tumor with divergent differentiation: cytologic, histologic, and ultrastructural findings.具有异向分化的小圆细胞肿瘤：细胞学、组织学及超微结构表现
Diagn Cytopathol. 1994;11(2):159-64. doi: 10.1002/dc.2840110210.
10
Effusion cytology of desmoplastic small round cell tumor of the pleura. A case report.胸膜促纤维增生性小圆细胞肿瘤的积液细胞学：一例报告
Acta Cytol. 1993 Jan-Feb;37(1):77-82.