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终末期肾病中的血色素沉着症:当废弃物成为一种治疗选择时。

Haemochromatosis in end-stage renal disease: when waste is a treatment option.

作者信息

Oettl Tobias, Dickenmann Michael

机构信息

Transplantation Immunology and Nephrology , University Hospital , Basel , Switzerland.

出版信息

NDT Plus. 2009 Feb;2(1):43-5. doi: 10.1093/ndtplus/sfn161. Epub 2008 Oct 21.

Abstract

For patients with end-stage renal disease and hereditary haemochromatosis, prevention and treatment of anaemia differ from usual nephrologic guidelines. Monitoring of individual disease progression and ferritin levels is crucial. We describe a case of a young haemodialysis patient with early-stage organ dysfunction caused by hereditary haemochromatosis, in whom iron stores have successfully been depleted with phlebotomy and supplemental erythropoietin over 22 months. Target ferritin levels could finally be reached without severe, persisting or symptomatic anaemia.

摘要

对于终末期肾病和遗传性血色素沉着症患者,贫血的预防和治疗不同于常规的肾脏病学指南。监测个体疾病进展和铁蛋白水平至关重要。我们描述了一例年轻的血液透析患者,其因遗传性血色素沉着症导致早期器官功能障碍,通过放血和补充促红细胞生成素,在22个月内成功耗尽了铁储备。最终达到了目标铁蛋白水平,且未出现严重、持续或有症状的贫血。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/553f/4421493/4f7992c0f4e2/sfn161fig1.jpg

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