Yamazaki Osamu, Hanafusa Norio, Yamada Atsuo, Noiri Eisei, Fujita Toshiro
Center of Hemodialysis and Apheresis.
Department of Gastroenterology , The University of Tokyo Hospital , Japan.
NDT Plus. 2009 Dec;2(6):469-72. doi: 10.1093/ndtplus/sfp111. Epub 2009 Aug 26.
Gastrointestinal (GI) bleeding is a common and troublesome complication of end-stage renal disease (ESRD). Patients often have various lesions in the small bowel and in either upper or lower GI tracts. Recently developed double-balloon endoscopy (DBE) enables observation of the entire small intestine through a combination of anterograde and retrograde approaches. Moreover, DBE is useful not only for diagnosis of small intestinal lesions; it provides a mode of treating the disease. This article presents patients with several small intestinal diseases from our facility. Their bleeding sources were identified using DBE. We also report two representative cases of angiodysplasia that had been diagnosed and treated successfully using DBE. One case particularly underscored the usefulness of the combination of capsule endoscopy (CE) and DBE as an electively diagnostic approach for patients with GI bleeding. Small intestinal bleeding is often observable repeatedly in a single patient, as described for case 1. In such circumstances, DBE can treat the lesions successfully without surgical procedures. In this report, ESRD patients, in whom comorbid conditions made it difficult to perform surgical procedures, receive great benefit from DBE.
胃肠道(GI)出血是终末期肾病(ESRD)常见且棘手的并发症。患者小肠以及上消化道或下消化道常存在各种病变。最近研发的双气囊内镜检查(DBE)通过顺行和逆行相结合的方法能够观察整个小肠。此外,DBE不仅对小肠病变的诊断有用;它还提供了一种治疗疾病的方式。本文介绍了我们机构中患有几种小肠疾病的患者。通过DBE确定了他们的出血来源。我们还报告了两例使用DBE成功诊断和治疗的血管发育异常典型病例。其中一个病例特别强调了胶囊内镜检查(CE)和DBE联合作为胃肠道出血患者选择性诊断方法的有用性。如病例1所述,小肠出血在单个患者中常可反复观察到。在这种情况下,DBE无需手术即可成功治疗病变。在本报告中,患有合并症而难以进行手术的ESRD患者从DBE中获益匪浅。