Verma Sadhika, Attallah Marline A, Jarrin Jara Maria Daniela, Gautam Avneesh S, Khan Safeera
Internal Medicine, California Institute of Behavorial Neurosciences and Psychology, Fairfield, USA.
Internal Medicine, California Institute of Behavorial Neurosciences and Psychology, Fairfiled, USA.
Cureus. 2020 Aug 16;12(8):e9784. doi: 10.7759/cureus.9784.
Gastrointestinal bleeding due to angiodysplasia is a common problem in patients with renal insufficiency. There are several theories to explain the increased occurrence of these lesions in this specific group of patients, including various metabolic factors and existence of comorbidities. Advancements made in diagnostic measures have helped route the approach in patients with different risk factors and have also helped solve the dual purpose involving therapeutic intervention with endoscopy. We conducted a thorough literature search on PubMed to extract relevant data. A total of 29 articles were chosen after applying the inclusion and exclusion criteria. Although the clinical presentations may vary in this cohort of patients, and bleeding is known to stop spontaneously, a conservative approach may not be enough. Endoscopic treatment, use of hormones like estrogen, octreotide, and vasopressin, arterial embolization, and lastly surgery are valuable therapeutic tools.
血管发育异常所致的胃肠道出血是肾功能不全患者的常见问题。有几种理论来解释这些病变在这一特定患者群体中发生率增加的原因，包括各种代谢因素和合并症的存在。诊断措施的进步有助于针对不同风险因素的患者制定治疗方案，也有助于解决涉及内镜治疗干预的双重目的。我们在PubMed上进行了全面的文献检索以提取相关数据。应用纳入和排除标准后共选择了29篇文章。尽管该患者群体的临床表现可能有所不同，且已知出血可自发停止，但保守治疗方法可能并不足够。内镜治疗、使用雌激素、奥曲肽和血管加压素等激素、动脉栓塞以及最后的手术都是有价值的治疗手段。
