家庭血液透析的结果：登记挑战。
Outcomes on home haemodialysis: registry challenges.
作者信息
MacGregor Mark S
机构信息
John Stevenson Lynch Renal Unit, NHS Ayrshire & Arran, Crosshouse Hospital, Kilmarnock, Scotland.
出版信息
NDT Plus. 2011 Dec;4(Suppl 3):iii32-iii35. doi: 10.1093/ndtplus/sfr126.
Abstract
Health care policy is encouraging expansion of home haemodialysis, aiming to improve patient outcomes and reduce cost. However, most patient outcome data derive from retrospective observational studies, with all their inherent weaknesses. Conventional thrice weekly home haemodialysis delivers a 22-51% reduction in mortality, but why should that be? Frequent and/or nocturnal haemodialysis reduces mortality by 36-66%, with comparable outcomes to deceased donor kidney transplantation. Approaches which might improve the quality of future observational studies are discussed. Patient-relevant outcomes other than mortality are also discussed.
摘要
医疗保健政策正在鼓励扩大家庭血液透析，旨在改善患者预后并降低成本。然而，大多数患者预后数据来自回顾性观察性研究，存在其固有的所有弱点。传统的每周三次家庭血液透析可使死亡率降低22%至51%，但为何会如此呢？频繁和/或夜间血液透析可使死亡率降低36%至66%，其结果与 deceased donor kidney transplantation相当。文中讨论了可能提高未来观察性研究质量的方法。还讨论了除死亡率之外与患者相关的其他预后情况。 （注：这里的“deceased donor kidney transplantation”直接保留英文未翻译，因为不太明确其准确的中文专业术语表述，若有更准确的专业词汇可替换）
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